h-prune Inhibitors
H-prune inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the h-prune protein, which is a member of the DHH (Asp-Glu-His-His) phosphoesterase family. H-prune is involved in important cellular processes such as cell motility, migration, and signal transduction. It possesses phosphodiesterase activity, meaning it can break down cyclic nucleotides like cAMP, a molecule that plays a key role in various signaling pathways. By inhibiting h-prune's enzymatic function, these inhibitors disrupt its role in regulating intracellular signaling cascades, leading to altered cell motility and migration dynamics. H-prune inhibitors are particularly valuable for studying how cells coordinate movement and respond to environmental cues at the molecular level.
Research on h-prune inhibitors focuses on understanding how this protein interacts with other molecular components that regulate the cytoskeleton and cell movement. By blocking h-prune, scientists can investigate how this protein influences actin filament assembly, focal adhesion dynamics, and other key aspects of cellular structure. Furthermore, h-prune inhibition allows for the study of its involvement in intracellular signaling pathways that affect cell communication, proliferation, and organization. These inhibitors are also useful in exploring how h-prune contributes to broader physiological processes such as tissue development and regeneration. By modulating h-prune activity, researchers can gain insights into the complex networks that govern cellular motility and the structural rearrangements necessary for cells to adapt to their surrounding environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A may downregulate h-prune expression by inhibiting histone deacetylases, leading to a more open chromatin structure and altered transcriptional activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine could decrease h-prune levels by inducing DNA demethylation in the gene promoter region, thereby reducing the transcriptional repression of the h-prune gene. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has the potential to suppress h-prune expression through inhibition of the NF-κB pathway, which could lead to reduced transcription of the h-prune gene. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may attenuate h-prune expression by hindering pathways involved in inflammation and cell proliferation, thereby leading to a decrease in h-prune levels. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein might lower h-prune expression by targeting and inhibiting specific tyrosine kinases, thereby disrupting downstream signaling pathways that control gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is known to suppress h-prune expression by its antioxidant property that can lead to the stabilization of cellular environments, thereby reducing h-prune levels. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Epigallocatechin Gallate may inhibit h-prune expression by obstructing pathways that control cell cycle progression and apoptosis, ultimately leading to reduced cellular levels of h-prune. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane could lead to a reduction in h-prune expression by activating cellular defense mechanisms that can lead to the degradation of h-prune mRNA. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Indole-3-carbinol might decrease h-prune expression by shifting estrogen metabolism, which may lead to changes in the expression patterns of genes like h-prune. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY 294002 has the potential to decrease h-prune expression by directly inhibiting PI3K, subsequently downregulating the Akt pathway, which is implicated in h-prune expression. | ||||||