Date published: 2026-1-10

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GYKL1 Inhibitors

GYKL1 inhibitors belong to a specific class of chemical compounds designed to modulate the activity of the GYKL1 protein. GYKL1 is a relatively obscure protein, and detailed information about its functions and roles within biological processes is limited. The precise functions of GYKL1 are still under investigation, and researchers are actively working to elucidate its significance within cellular and biochemical contexts. GYKL1 inhibitors are developed with the primary aim of selectively interacting with the GYKL1 protein, potentially influencing its activity and, in turn, impacting downstream cellular processes.

Typically, GYKL1 inhibitors consist of small molecules or chemical compounds specifically engineered to bind to GYKL1, targeting either its active site or allosteric sites. This interaction can lead to the modulation of GYKL1's behavior, potentially affecting its involvement in various cellular processes, although the exact pathways and functions influenced by GYKL1 are not yet well-defined. Researchers are primarily focused on unraveling the biological roles and mechanisms of GYKL1 and how inhibiting its activity with these compounds may provide insights into cell biology and biochemical pathways. The development of GYKL1 inhibitors represents an ongoing area of research within the field of molecular pharmacology and biochemistry, contributing to our broader understanding of cellular processes and the functions of less-studied proteins like GYKL1.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide may interfere with transcription factor activity, potentially downregulating the expression of genes like Gk.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This agent can incorporate into DNA and RNA, leading to hypomethylation of DNA and potentially reducing the expression of genes.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

Mithramycin A binds to GC-rich DNA sequences, potentially preventing transcriptional activation of certain genes.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits mTOR, a kinase that regulates protein synthesis and may indirectly affect gene expression profiles.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$275.00
$474.00
$1639.00
$2497.00
$5344.00
4
(1)

Rocaglamide inhibits translation initiation, potentially decreasing the synthesis of certain proteins.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine intercalates into DNA, which may inhibit DNA and RNA synthesis and thereby reduce gene transcription.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting RNA polymerase movement and thus mRNA synthesis.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

α-Amanitin is a potent inhibitor of RNA polymerase II, which is essential for mRNA synthesis.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

DRB inhibits RNA polymerase II's transcriptional elongation, which may reduce gene expression.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

Flavopiridol inhibits cyclin-dependent kinases, which are key for RNA polymerase II function and gene expression.