GTPBP3 Activators
The suite of chemicals regarded as GTPBP3 activators underscores a central theme: fostering an environment conducive to mitochondrial health and function, thereby indirectly enhancing the role of GTPBP3 in tRNA modification. Mitochondrial health and resilience, essential for myriad cellular activities, play a pivotal role in ensuring the optimal function of proteins like GTPBP3 localized within this organelle. Agents such as Coenzyme Q10, central to mitochondrial energy production, and MitoQ, a mitochondria-targeted antioxidant, work in concert to bolster the electron transport chain and shield mitochondria from oxidative damage, respectively. These actions, in unison, can indirectly catalyze GTPBP3's function, ensuring tRNA modification processes proceed seamlessly.
Complementary to this, chemicals like DCA (Dichloroacetate) and EPI-589 influence specific mitochondrial processes, with the former acting on pyruvate dehydrogenase (PDH) and the latter modulating the mitochondrial redox environment. In this optimized environment, GTPBP3 is well-equipped to undertake its tRNA modification function. Augmenting this, the strategic utilization of agents like SS-31 (Elamipretide), targeting the inner mitochondrial membrane, and NMN, a precursor of the crucial NAD+, further accentuate mitochondrial health. By facilitating optimal mitochondrial conditions through direct and indirect interventions, the selected chemicals ensure that GTPBP3's role in mitochondrial tRNA modification is adequately supported, emphasizing the critical nature of mitochondrial health and function in influencing associated proteins.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
A coenzyme crucial for mitochondrial energy production. Coenzyme Q10 supports the electron transport chain, indirectly facilitating mitochondrial tRNA processes, possibly augmenting GTPBP3 function in tRNA modification. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
A mitochondria-targeted antioxidant. By protecting mitochondria from oxidative damage, MitoQ can ensure optimal conditions for GTPBP3-mediated tRNA modification. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $60.00 $125.00 | 5 | |
Influences pyruvate dehydrogenase (PDH) by inhibiting the enzyme pyruvate dehydrogenase kinase. Activation of PDH can lead to enhanced mitochondrial function, indirectly supporting GTPBP3's role in tRNA modification. | ||||||
Elamipretide | 736992-21-5 | sc-507453 | 25 mg | $670.00 | ||
Targets the inner mitochondrial membrane, enhancing electron transport and reducing oxidative damage. SS-31 indirectly promotes a milieu within the mitochondria supportive of GTPBP3's tRNA modification function. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
A central electron carrier in mitochondrial respiration. Elevated NADH levels can enhance mitochondrial functions, indirectly benefiting GTPBP3's role in mitochondrial tRNA modification. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
A precursor of NAD+, crucial for mitochondrial health. By supporting NAD+ synthesis, NMN indirectly bolsters mitochondrial processes, including those involving GTPBP3. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
Supports mitochondrial biogenesis. By promoting the generation of new mitochondria, PQQ indirectly augments the functional capacity for tRNA modifications mediated by GTPBP3. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
Activator of SIRT1, a protein known to enhance mitochondrial function. Indirectly, SR4's activation of SIRT1 can enhance GTPBP3's efficiency in tRNA modification by promoting mitochondrial health. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Activates AMPK, which is associated with enhanced mitochondrial biogenesis and function. By promoting mitochondrial health, Metformin can indirectly support GTPBP3's role in tRNA modification. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
SIRT1 activator that can indirectly promote mitochondrial health. Enhanced mitochondrial function can provide optimal conditions for GTPBP3's activity in mitochondrial tRNA modification. | ||||||