GRSP1 Activators
GRSP1 Activators comprise a specialized category of chemical compounds designed to selectively enhance the activity of GRSP1, a protein whose biological functions and roles are currently under active investigation within the scientific community. GRSP1, also known as C14orf159, belongs to a group of relatively understudied proteins, and its designation as a "C14orf" (Chromosome 14 open reading frame) implies its classification as a protein with an unknown function. The development of GRSP1 Activators represents a significant research endeavor aimed at uncovering the protein's functions and potential involvement in cellular processes. These activators are synthesized through intricate chemical engineering processes, with the aim of producing molecules that can specifically interact with GRSP1, potentially modulating its activity or revealing its endogenous ligands. The effective design of GRSP1 Activators requires a deep understanding of the protein's structure, including any functional domains or motifs that may be targeted for modulation.
The study of GRSP1 Activators involves a multidisciplinary research approach, combining techniques from molecular biology, biochemistry, and structural biology to understand how these compounds interact with GRSP1. Scientists employ protein expression and purification methods to obtain GRSP1 for further analysis. Functional assays, including cellular experiments and enzymatic assays, are employed to evaluate the impact of activators on GRSP1-mediated cellular processes or interactions with other molecules. Structural studies, such as X-ray crystallography or cryo-electron microscopy, play a pivotal role in determining the three-dimensional structure of GRSP1, identifying potential activator binding sites, and elucidating the conformational changes associated with activation. Computational modeling and molecular docking further aid in predicting the interactions between GRSP1 and potential activators, guiding the rational design and optimization of these molecules for increased specificity and efficacy. Through this comprehensive research effort, the study of GRSP1 Activators aims to advance our understanding of the protein's function and its potential relevance in cellular biology, contributing to the broader field of protein characterization and cellular mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC) which is involved in numerous signal transduction pathways that can modulate gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises intracellular cAMP levels, which can lead to the activation of the cAMP response element-binding protein (CREB) and alteration of gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium can inhibit GSK3β, potentially affecting Wnt signaling and gene expression patterns, including those of FERM domain proteins. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Acts through retinoic acid receptors to regulate gene expression and might indirectly affect FRMD4B expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, it can modulate gene expression through glucocorticoid response elements in target genes. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor potentially affecting the methylation status of genes and their expression profiles. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can lead to the accumulation of regulatory proteins, potentially affecting gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Histone deacetylase inhibitor that can influence chromatin structure and gene expression. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
Often used as a solvent, DMSO can also modulate gene expression and cellular differentiation processes. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A protein kinase inhibitor that may alter multiple signaling pathways and potentially affect gene expression. | ||||||