Date published: 2025-9-9

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GRO1 Inibidores

GRO1 inhibitors are a distinct class of chemical compounds that function by targeting and inhibiting the activity of the Growth-regulated oncogene 1 (GRO1) protein. GRO1, also known as CXCL1, is a chemokine involved in various cellular processes including cell proliferation, migration, and angiogenesis. The inhibition of GRO1 can result in the modulation of signaling pathways that regulate these fundamental cellular activities. GRO1 inhibitors typically achieve this by binding to the GRO1 protein or its receptor, CXCR2, thereby blocking the interaction and subsequent downstream signaling cascades. This blockade can alter the expression of various genes and proteins involved in the regulation of the cell cycle, apoptosis, and other cellular mechanisms.

In the realm of biochemical research, GRO1 inhibitors are instrumental in elucidating the underlying mechanisms of GRO1-related cellular processes. They serve as crucial tools in studying the regulatory networks influenced by GRO1 and its associated signaling pathways. By modulating GRO1 activity, researchers can gain insights into the protein's role in cellular dynamics and its broader implications in tissue homeostasis and pathology. Moreover, GRO1 inhibitors are often employed in various experimental models to investigate the effects of GRO1 inhibition on cell behavior, including changes in gene expression profiles, alterations in cellular morphology, and impacts on cell-cell communication. Through such studies, GRO1 inhibitors contribute significantly to our understanding of the molecular basis of cellular functions and the intricate web of signaling pathways governing these processes.

VEJA TAMBÉM

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Reparixin

266359-83-5sc-507446
5 mg
$76.00
(0)

A reparixina é um antagonista de pequenas moléculas que tem como alvo o recetor CXCR1, que é o recetor primário para a CXCLI e demonstrou efeitos inibitórios na inflamação induzida pela CXCL1 e no recrutamento de neutrófilos.

AZD 5069

878385-84-3sc-507447
5 mg
$230.00
(0)

O AZD5069 é um antagonista seletivo de pequenas moléculas de CXCRIt que demonstrou efeitos inibitórios na migração de neutrófilos mediada por CXCL1 e tem sido investigado em doenças pulmonares inflamatórias.

SB 225002

182498-32-4sc-202803
sc-202803A
1 mg
5 mg
$35.00
$100.00
2
(1)

O SB225002 é um antagonista de pequenas moléculas que tem como alvo o CXCRIt e demonstrou efeitos inibidores na ativação e migração de neutrófilos induzida pelo CXCL1.