Date published: 2026-1-30

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GRHL Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GRHL Antibodies for investigating Grainyhead-like (GRHL) proteins in research applications. GRHL Antibodies are validated for multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GRHL proteins function as transcription factors that regulate epithelial development and maintenance. Research has shown that GRHL proteins significantly influence cell differentiation, migration, and tissue integrity. Understanding GRHL protein activity provides insights into various biological pathways and disease mechanisms. Cancer research has revealed that alterations in GRHL protein expression can impact tumor progression and metastasis. Investigating GRHL proteins advances knowledge in developmental biology, tissue homeostasis, and disease pathology. Current research continues to uncover new roles for GRHL proteins in cellular processes and signaling pathways. Santa Cruz Biotechnology monoclonal antibodies for GRHL proteins enable researchers worldwide to make meaningful discoveries that advance scientific understanding.

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GRHL Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GRHL1 Antibody (D-2)

sc-515541mouse IgG1 κ117-180 (h)WB, IP, IF, ELISAm, r, h
1
(1)

GRHL3 Antibody (C-12)

sc-398838mouse IgG2b κ435-459 (h)WB, IP, IF, ELISAm, r, h
6
(8)

GRHL CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GRHL2 CRISPR/Cas9 KO Plasmid (h)

sc-408284hGene KnockoutGFP
1
(0)

GRHL2 HDR Plasmid (h)

sc-408284-HDRhHomology Directed RepairPuromycin
1
(0)

GRHL2 CRISPR/Cas9 KO Plasmid (m)

sc-434250mGene KnockoutGFP
1
(0)

GRHL2 HDR Plasmid (m)

sc-434250-HDRmHomology Directed RepairPuromycin
1
(0)

GRHL3 CRISPR/Cas9 KO Plasmid (h)

sc-404946hGene KnockoutGFP0
(0)

GRHL CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GRHL2 CRISPR Activation Plasmid (h)

sc-408284-ACThGene ActivationPuro, Blast, Hygro
1
(0)

GRHL2 CRISPR Activation Plasmid (h2)

sc-408284-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

GRHL2 CRISPR Activation Plasmid (m)

sc-434250-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

GRHL2 CRISPR Activation Plasmid (m2)

sc-434250-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

GRHL siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GRHL1 siRNA (h)

sc-95046hGene SilencingN/A0
(0)

GRHL1 shRNA Plasmid (h)

sc-95046-SHhGene SilencingPuromycin0
(0)

GRHL1 shRNA (h) Lentiviral Particles

sc-95046-VhGene SilencingPuromycin0
(0)

GRHL2 siRNA (h)

sc-77606hGene SilencingN/A
4
(0)

GRHL2 shRNA Plasmid (h)

sc-77606-SHhGene SilencingPuromycin
4
(0)

GRHL2 shRNA (h) Lentiviral Particles

sc-77606-VhGene SilencingPuromycin
4
(0)

GRHL2 siRNA (m)

sc-145761mGene SilencingN/A0
(0)

GRHL3 siRNA (h)

sc-78890hGene SilencingN/A0
(0)

GRHL3 shRNA Plasmid (h)

sc-78890-SHhGene SilencingPuromycin0
(0)

GRHL3 shRNA (h) Lentiviral Particles

sc-78890-VhGene SilencingPuromycin0
(0)

GRHL3 siRNA (m)

sc-145762mGene SilencingN/A0
(0)

GRHL3 shRNA Plasmid (m)

sc-145762-SHmGene SilencingPuromycin0
(0)

GRHL3 shRNA (m) Lentiviral Particles

sc-145762-VmGene SilencingPuromycin0
(0)