Gm14137 Activators
Gm14137, a predicted gene in Mus musculus (house mouse), is believed to play a role in various cellular processes, including Rho protein signal transduction, positive regulation of cellular component biogenesis, and regulation of cell shape. It is predicted to be located in the mitochondrion and active in the cytoplasm, cytoskeleton, and plasma membrane. While the exact function of Gm14137 remains to be fully characterized, its involvement in these processes suggests it may play a critical role in cellular structure and signaling.
The activation of Gm14137 can potentially be influenced by a range of chemicals. For instance, retinoic acid, by regulating genes associated with Rho protein signaling and cellular component biogenesis, may indirectly enhance Gm14137 expression. Similarly, forskolin, through cAMP-mediated pathways, can modulate processes related to Gm14137's functions. Epidermal Growth Factor (EGF) can initiate signaling cascades affecting cellular processes associated with Gm14137. Insulin, by activating PI3K/Akt pathways, may impact cytoskeletal dynamics and plasma membrane functions, indirectly influencing Gm14137. Histone deacetylase inhibitors like sodium butyrate and sodium valproate can modify epigenetic regulation, potentially affecting Gm14137 expression by altering chromatin structure. Ionomycin, which elevates intracellular calcium, may modulate processes related to Rho protein signal transduction, a function predicted for Gm14137. These examples demonstrate the diverse mechanisms through which various chemicals can potentially activate Gm14137, shedding light on its potential role in cellular structure and signaling. Further research is needed to fully elucidate the precise functions and activation mechanisms of Gm14137 in mouse biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a Vitamin A metabolite, binds to nuclear receptors, impacting gene expression. It may indirectly stimulate Gm14137 expression by regulating genes involved in Rho protein signal transduction and cellular component biogenesis, processes predicted to involve Gm14137. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates PI3K/Akt pathways, which can modulate cytoskeleton dynamics and plasma membrane functions. This activation might indirectly upregulate Gm14137 by influencing processes linked to its predicted functions, such as regulation of cell shape and cellular component biogenesis. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, a histone deacetylase inhibitor, can affect epigenetic regulation. It may indirectly stimulate Gm14137 expression by altering chromatin structure and accessibility to the gene's promoter region, impacting processes associated with Gm14137, including Rho protein signaling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride activates GSK-3β, a kinase associated with the Wnt signaling pathway. While Wnt ligands are excluded per your instructions, downstream targets of Wnt signaling, including processes related to cellular component biogenesis and cell shape, may be indirectly influenced by lithium chloride. | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $385.00 $2654.00 | ||
Vitamin A can be converted to retinoic acid intracellularly. It may indirectly stimulate Gm14137 by serving as a source for retinoic acid, which regulates gene expression related to Rho protein signaling and cellular component biogenesis, processes associated with Gm14137. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin, a calcium ionophore, elevates intracellular calcium levels, impacting various signaling pathways. Increased calcium can indirectly influence Gm14137 by modulating processes related to Rho protein signal transduction, a function predicted for Gm14137. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyric acid, a short-chain fatty acid, can affect histone acetylation and gene expression. It may indirectly stimulate Gm14137 expression by modifying chromatin structure, potentially impacting processes linked to Gm14137, such as regulation of cell shape and cellular component biogenesis. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Nicotinic Acid activates GPR109A, impacting cellular metabolism. This activation might indirectly upregulate Gm14137 by influencing processes related to cellular component biogenesis and regulation of cell shape, functions associated with Gm14137. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid sodium salt, a histone deacetylase inhibitor, can alter epigenetic regulation. It may indirectly stimulate Gm14137 expression by modifying chromatin structure, affecting processes predicted for Gm14137, including positive regulation of cellular component biogenesis. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside, a precursor of NAD+, can activate sirtuins, influencing cellular metabolism. This activation might indirectly upregulate Gm14137 by impacting processes related to regulation of cell shape and plasma membrane, functions associated with Gm14137. | ||||||