Date published: 2025-12-24

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GluR-3 Inhibitors

GluR-3 inhibitors encompass a specific category of chemical compounds that modulate the function of GluR-3, a subunit of ionotropic glutamate receptors. These receptors play a pivotal role in orchestrating excitatory neurotransmission within the central nervous system, influencing fundamental processes of synaptic communication. GluR-3, as a constituent of these receptors, contributes to the intricacies of synaptic transmission and synaptic plasticity, integral to the dynamics of learning and memory. These inhibitors are artfully engineered to interact with precise molecular motifs within GluR-3, thus perturbing its function and altering its involvement in neuronal signaling. Characterized by their diverse structural architectures, GluR-3 inhibitors exhibit an array of chemical frameworks, each tailored with unique chemical elements that facilitate targeted binding to specific sites on GluR-3. Through these interactions, GluR-3 inhibitors hold promise for unraveling the complexities of neuronal communication and synaptic modulation. As ongoing research delves deeper into the intricacies of GluR-3 inhibition, the exploration of novel avenues in the realm of neurotransmission continues to unfold.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Philanthotoxin 74

401601-12-5sc-204189
sc-204189A
1 mg
10 mg
$91.00
$189.00
(1)

Philanthotoxin 74 acts as a selective antagonist of the glur-3 receptor, exhibiting a unique binding affinity that disrupts typical glutamate signaling pathways. Its distinct molecular architecture enables it to engage with specific receptor domains, leading to altered ion permeability and modulation of synaptic plasticity. The compound's interaction kinetics reveal a slow dissociation rate, contributing to prolonged effects on neuronal activity and influencing excitatory synaptic transmission dynamics.

IEM 1460

121034-89-7sc-204007
sc-204007A
10 mg
50 mg
$128.00
$520.00
(0)

IEM-1460 is a synthetic compound that has shown inhibitory effects on GluR-3-containing AMPA receptors, potentially affecting glutamatergic neurotransmission.