Date published: 2025-11-24

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GluR-1 Antibodies

Santa Cruz Biotechnology offers a broad range of GluR-1 monoclonal antibodies for research focused on understanding GluR-1's role in synaptic transmission and plasticity. GluR-1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GluR-1, a subunit of the AMPA receptor, plays a critical role in mediating fast excitatory neurotransmission in the central nervous system. Proper GluR-1 functioning is essential for synaptic plasticity, learning, and memory processes. Research has shown that GluR-1 expression levels significantly impact neural communication and cognitive function. Dysregulation of GluR-1 has been implicated in various neurological disorders, making it a significant target for research in neurobiology. Understanding GluR-1's molecular mechanisms can provide valuable insights into potential therapeutic strategies for neurological conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance neuroscience research and contribute to breakthrough discoveries in neural function and disease treatment.

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GluR-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GluR-1 Antibody (G-12)

sc-55509mouse IgG1 κN-Terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
39
(14)

GluR-1 Antibody (E-6)

sc-13152mouse IgG1 κ33-51 (h)WB, IP, IF, ELISAm, r, h
50
(12)

GluR-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GluR-1 CRISPR/Cas9 KO Plasmid (h)

sc-416424hGene KnockoutGFP0
(0)

GluR-1 HDR Plasmid (h)

sc-416424-HDRhHomology Directed RepairPuromycin0
(0)

GluR-1 Double Nickase Plasmid (h)

sc-416424-NIChGene KnockoutPuromycin0
(0)

GluR-1 Double Nickase Plasmid (h2)

sc-416424-NIC-2hGene KnockoutPuromycin0
(0)

GluR-1 CRISPR/Cas9 KO Plasmid (m)

sc-420679mGene KnockoutGFP0
(0)

GluR-1 HDR Plasmid (m)

sc-420679-HDRmHomology Directed RepairPuromycin0
(0)

GluR-1 Double Nickase Plasmid (m)

sc-420679-NICmGene KnockoutPuromycin0
(0)

GluR-1 Double Nickase Plasmid (m2)

sc-420679-NIC-2mGene KnockoutPuromycin0
(0)

GluR-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GluR-1 CRISPR Activation Plasmid (h)

sc-416424-ACThGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 CRISPR Activation Plasmid (h2)

sc-416424-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 Lentiviral Activation Particles (h)

sc-416424-LAChGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 Lentiviral Activation Particles (h2)

sc-416424-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 CRISPR Activation Plasmid (m)

sc-420679-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 CRISPR Activation Plasmid (m2)

sc-420679-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 Lentiviral Activation Particles (m)

sc-420679-LACmGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 Lentiviral Activation Particles (m2)

sc-420679-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GluR-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GluR-1 siRNA (h)

sc-35485hGene SilencingN/A
2
(0)

GluR-1 shRNA Plasmid (h)

sc-35485-SHhGene SilencingPuromycin
2
(0)

GluR-1 shRNA (h) Lentiviral Particles

sc-35485-VhGene SilencingPuromycin
2
(0)

GluR-1 siRNA (m)

sc-35486mGene SilencingN/A0
(0)

GluR-1 shRNA Plasmid (m)

sc-35486-SHmGene SilencingPuromycin0
(0)

GluR-1 shRNA (m) Lentiviral Particles

sc-35486-VmGene SilencingPuromycin0
(0)

GluR-1 siRNA (r)

sc-270586rGene Silencing0
(0)

GluR-1 shRNA Plasmid (r)

sc-270586-SHrGene Silencing0
(0)

GluR-1 shRNA (r) Lentiviral Particles

sc-270586-VrGene SilencingPuromycin0
(0)