Glucosidase IIβ (GluIIβ) is a part of the Glucosidase II enzyme, which is involved in the processing of N-linked oligosaccharides of glycoproteins in the endoplasmic reticulum. Glucosidase IIβ Activators represent a class of chemicals that can influence the function of Glucosidase IIβ indirectly. These compounds exert their effects through their influence on related cellular processes such as vesicular transport, intracellular trafficking, and glycan processing.
Chemicals such as Tunicamycin, Brefeldin A, Monensin, Nocodazole, Taxol, Okadaic acid, Calyculin A, Tautomycetin, Forskolin, Ionomycin, Thapsigargin, and Cyclin-dependent kinase inhibitors can potentially influence Glucosidase IIβ function through their effects on these processes. The effects of these chemicals on Glucosidase IIβ function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, which can indirectly affect Glucosidase IIβ by influencing protein maturation and transport. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A is a fungal metabolite that disrupts transport from the ER to the Golgi apparatus. It can indirectly affect Glucosidase IIβ by modifying the vesicular transport processes. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin is an ionophore that disrupts vesicular transport. It can indirectly affect Glucosidase IIβ by modifying the vesicular transport processes. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, thus affecting vesicular transport. It can indirectly affect Glucosidase IIβ function by influencing cellular transport processes. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol stabilizes microtubules and thus can indirectly influence Glucosidase IIβ by affecting vesicular transport processes. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence Glucosidase IIβ by affecting cellular phosphorylation states. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence Glucosidase IIβ by affecting cellular phosphorylation states. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing intracellular cAMP levels and potentially influencing vesicular transport processes that involve Glucosidase IIβ. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that can indirectly influence Glucosidase IIβ by triggering calcium-dependent signaling pathways. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a non-competitive inhibitor of the sarco-/endoplasmic reticulum Ca2+ ATPase (SERCA) and can indirectly influence Glucosidase IIβ by modifying intracellular calcium levels. | ||||||