Date published: 2026-4-24

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Glucosidase IIβ Activators

Glucosidase IIβ (GluIIβ) is a part of the Glucosidase II enzyme, which is involved in the processing of N-linked oligosaccharides of glycoproteins in the endoplasmic reticulum. Glucosidase IIβ Activators represent a class of chemicals that can influence the function of Glucosidase IIβ indirectly. These compounds exert their effects through their influence on related cellular processes such as vesicular transport, intracellular trafficking, and glycan processing.

Chemicals such as Tunicamycin, Brefeldin A, Monensin, Nocodazole, Taxol, Okadaic acid, Calyculin A, Tautomycetin, Forskolin, Ionomycin, Thapsigargin, and Cyclin-dependent kinase inhibitors can potentially influence Glucosidase IIβ function through their effects on these processes. The effects of these chemicals on Glucosidase IIβ function are context-dependent and may vary based on the cellular environment and other biochemical parameters.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Tunicamycin inhibits N-linked glycosylation, which can indirectly affect Glucosidase IIβ by influencing protein maturation and transport.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Brefeldin A is a fungal metabolite that disrupts transport from the ER to the Golgi apparatus. It can indirectly affect Glucosidase IIβ by modifying the vesicular transport processes.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

Monensin is an ionophore that disrupts vesicular transport. It can indirectly affect Glucosidase IIβ by modifying the vesicular transport processes.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

Nocodazole disrupts microtubules, thus affecting vesicular transport. It can indirectly affect Glucosidase IIβ function by influencing cellular transport processes.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Taxol stabilizes microtubules and thus can indirectly influence Glucosidase IIβ by affecting vesicular transport processes.

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$291.00
$530.00
$1800.00
78
(4)

Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence Glucosidase IIβ by affecting cellular phosphorylation states.

Calyculin A

101932-71-2sc-24000
sc-24000A
10 µg
100 µg
$163.00
$800.00
59
(3)

Calyculin A is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence Glucosidase IIβ by affecting cellular phosphorylation states.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylyl cyclase, increasing intracellular cAMP levels and potentially influencing vesicular transport processes that involve Glucosidase IIβ.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin is a calcium ionophore that can indirectly influence Glucosidase IIβ by triggering calcium-dependent signaling pathways.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin is a non-competitive inhibitor of the sarco-/endoplasmic reticulum Ca2+ ATPase (SERCA) and can indirectly influence Glucosidase IIβ by modifying intracellular calcium levels.