Date published: 2026-5-7

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Glucosidase II alpha Inhibitors

Santa Cruz Biotechnology now offers a broad range of Glucosidase II alpha Inhibitors for use in various applications. These compounds are critical in the field of biochemical research due to their ability to inhibit Glucosidase II alpha, an enzyme involved in the N-glycan processing pathway. By modulating this enzyme's activity, researchers can study its role in the biosynthesis and maturation of glycoproteins, which are essential for cell-cell communication, protein folding, and stability. The inhibition of Glucosidase II alpha provides valuable insights into the quality control mechanisms within the endoplasmic reticulum and how cells ensure proper protein folding. This category of inhibitors is also instrumental in investigating the biochemical pathways and mechanisms of glycoprotein degradation and misfolding, which are crucial for understanding cellular homeostasis and the underlying causes of various biochemical disorders. The use of Glucosidase II alpha Inhibitors in scientific research enables the exploration of complex biochemical networks and contributes to the development of novel methodologies for studying protein-glycan interactions. These inhibitors are not only vital for basic research but also for applied sciences, including biotechnology and synthetic biology, where precise control over glycosylation processes can lead to advances in protein engineering and protein production. View detailed information on our available Glucosidase II alpha Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride

100991-92-2sc-220553
sc-220553A
10 mg
25 mg
$431.00
$1025.00
2
(1)

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride functions as a glucosidase II alpha inhibitor, exhibiting a distinctive ability to modulate glycoprotein maturation. Its structural features facilitate specific hydrogen bonding with the enzyme's active site, leading to altered catalytic efficiency. The compound's kinetic profile indicates competitive inhibition, impacting substrate turnover rates. Furthermore, its solubility characteristics may influence its interaction with cellular membranes, potentially affecting bioavailability and distribution within biological systems.

Deoxynojirimycin

19130-96-2sc-201369
sc-201369A
1 mg
5 mg
$73.00
$145.00
(0)

This is a natural compound isolated from mulberry leaves and is known to inhibit various glycosidases, including glucosidase IIα.

Castanospermine

79831-76-8sc-201358
sc-201358A
100 mg
500 mg
$184.00
$632.00
10
(1)

A natural alkaloid obtained from the chestnut tree, it has been studied for its inhibitory effects on glucosidase IIα.

Celgosivir

121104-96-9sc-488385
sc-488385A
sc-488385B
5 mg
25 mg
100 mg
$525.00
$902.00
$2700.00
(0)

While primarily investigated as an α-glucosidase I inhibitor, it may also have effects on glucosidase IIα.