GH-2 inhibitors constitute a distinct class of chemical compounds known for their ability to modulate the biological pathway associated with GH-2, or Growth Hormone 2. These inhibitors are meticulously crafted to exert influence over the actions of GH-2, a pivotal protein that governs a multitude of physiological functions. GH-2, primarily produced by the pituitary gland, plays a central role in overseeing growth and development, particularly during the formative years of childhood and adolescence. Furthermore, it wields significant control over metabolic equilibrium in adults. GH-2 inhibitors, whether synthetically engineered or naturally occurring, are compounds specifically designed to interfere with GH-2's signaling mechanisms and functions. Researchers are keenly interested in their potential to disrupt GH-2 signaling cascades, which could have far-reaching implications on processes such as growth regulation, metabolic homeostasis, and tissue regeneration. What sets GH-2 inhibitors apart from other inhibitor classes is their unique targeting of GH-2, differentiating them as invaluable tools for scientific investigation and offering the promise of innovative interventions in the future.
These inhibitors function through a spectrum of molecular mechanisms, each with the shared objective of perturbing the normal signaling cascade initiated by GH-2 binding to its receptor. This disruption can manifest at various stages within the GH-2 pathway, encompassing receptor binding, downstream signal transduction, or even hindrance of GH-2 synthesis and secretion.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
13C6-Lys octreotide tri(trifluoroacetate) | 83150-76-9 (unlabeled free base) | sc-477942 | 500 µg | $396.00 | ||
A synthetic peptide analog that binds to somatostatin receptors, inhibiting the release of GH from the pituitary gland. | ||||||
Bromocriptine | 25614-03-3 | sc-337602A sc-337602B sc-337602 | 10 mg 100 mg 1 g | $57.00 $265.00 $567.00 | 4 | |
Functions as a dopamine receptor agonist, inhibiting GH release by acting on the hypothalamus and reducing GHRH secretion. | ||||||
Cabergoline | 81409-90-7 | sc-203864 sc-203864A | 10 mg 50 mg | $300.00 $1055.00 | ||
Another dopamine receptor agonist that reduces GH secretion by inhibiting GHRH release from the hypothalamus. | ||||||