Gas1 Inhibitors
Gas1 inhibitors belong to a specific chemical class that primarily targets the growth arrest-specific 1 (Gas1) protein. Gas1 is a glycosylphosphatidylinositol (GPI)-anchored protein that plays a crucial role in regulating cell growth and differentiation. The inhibitors designed to modulate Gas1 function typically interfere with its signaling pathways, exerting their effects at the molecular level. These compounds are meticulously designed to interact with specific regions of the Gas1 protein, disrupting its normal cellular functions.
The Gas1 protein is known for its involvement in diverse cellular processes, including embryonic development, organogenesis, and tissue homeostasis. Inhibition of Gas1 can lead to alterations in cell cycle progression and differentiation, making Gas1 inhibitors potential tools for studying cellular growth control mechanisms. The structural design of Gas1 inhibitors is intricately crafted to ensure specificity and efficacy in selectively modulating Gas1 activity. Researchers working with Gas1 inhibitors aim to unravel the intricate molecular mechanisms that govern cellular growth, providing valuable insights into the fundamental processes underlying development and tissue maintenance.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GANT61 | 500579-04-4 | sc-202630 sc-202630A sc-202630B | 1 mg 5 mg 10 mg | $64.00 $131.00 $204.00 | 6 | |
Targets the downstream transcription factors of the Hh pathway, which Gas1 can impact. | ||||||
Robotnikinin | 1132653-79-2 | sc-396554 | 1 mg | $650.00 | 1 | |
Interferes with the interaction between Hh proteins and Gas1, disrupting signaling. | ||||||
Jervine | 469-59-0 | sc-200934 sc-200934A | 1 mg 5 mg | $66.00 $240.00 | 1 | |
Alters Hedgehog signaling similarly to cyclopamine and can affect the role of Gas1 in this pathway. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
A more potent variant of cyclopamine that can affect Gas1's modulation of Hh signaling. | ||||||
SANT-1 | 304909-07-7 | sc-203253 | 5 mg | $135.00 | 5 | |
A small molecule antagonist of the Hh signaling pathway, which could alter Gas1 activity. | ||||||
Vismodegib | 879085-55-9 | sc-396759 sc-396759A | 10 mg 25 mg | $82.00 $158.00 | 1 | |
An inhibitor of Smoothened, part of the Hh pathway that Gas1 is implicated in. | ||||||
Erismodegib | 956697-53-3 | sc-396280 sc-396280A | 10 mg 100 mg | $255.00 $918.00 | ||
Another Smoothened inhibitor that would indirectly affect Gas1's function in the Hh pathway. | ||||||