Date published: 2026-4-25

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Ganglioside GD2 Activators

Ganglioside GD2 Activators represent a class of chemical compounds associated with the modulation or enhancement of the biological activity of Ganglioside GD2, a glycosphingolipid molecule primarily found on the surface of cell membranes. Gangliosides are a subgroup of glycosphingolipids that contain sialic acid residues and play important roles in various cellular processes, including cell-cell recognition, signal transduction, and immune responses. Ganglioside GD2 is particularly abundant in neural tissues, as well as on the surface of certain cancer cells, making it an interesting target for research.

Ganglioside GD2 Activators are believed to interact with Ganglioside GD2, influencing its binding properties, membrane localization, or interactions with other molecules. These activators may impact cell signaling pathways, adhesion, or recognition events mediated by Ganglioside GD2. Understanding how Ganglioside GD2 Activators modulate the function of Ganglioside GD2 is essential for unraveling the intricate roles of glycosphingolipids in cellular physiology and pathophysiology. Research in this area contributes to our knowledge of cell surface glycolipid interactions, their impact on cell behavior, and their relevance in various biological contexts.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tamoxifen

10540-29-1sc-208414
2.5 g
$272.00
18
(2)

Tamoxifen, a selective estrogen receptor modulator, modulates ganglioside expression in certain cell types, potentially influencing GD2 levels.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibitor of MEK, indirectly influences the MAPK/ERK pathway, impacting ganglioside expression including GD2.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Disrupts the Golgi apparatus, influencing glycoprotein and glycolipid processing, potentially altering GD2 synthesis.

Manumycin A

52665-74-4sc-200857
sc-200857A
1 mg
5 mg
$219.00
$634.00
5
(1)

A farnesyltransferase inhibitor, affects cell signaling pathways, potentially impacting ganglioside synthesis including GD2.

Fumonisin B1

116355-83-0sc-201395
sc-201395A
1 mg
5 mg
$200.00
$680.00
18
(1)

Inhibits ceramide synthase, which could lead to altered ganglioside metabolism, indirectly affecting GD2 levels.