Date published: 2026-2-7

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gamma-GCSc Inhibitors

Santa Cruz Biotechnology now offers a broad range of gamma-GCSc Inhibitors for use in various applications. Gamma-glutamylcysteine synthetase (gamma-GCSc) is a key enzyme in the synthesis of glutathione, a critical antioxidant that helps maintain cellular redox balance and detoxify harmful substances. Gamma-GCSc Inhibitors are essential tools for studying the regulation of glutathione synthesis and understanding its role in cellular defense mechanisms against oxidative stress. In scientific research, gamma-GCSc Inhibitors are used to explore the effects of reduced glutathione synthesis on cellular redox states, apoptosis, and signaling pathways. These inhibitors help explain the role of glutathione in maintaining cellular homeostasis and its involvement in response to environmental stresses. Researchers employ gamma-GCSc Inhibitors to study the interactions between glutathione and other cellular components. Additionally, these inhibitors are valuable in high-throughput screening assays aimed at discovering new modulators of glutathione biosynthesis, aiding in the identification of novel regulatory mechanisms and potential research targets. The use of gamma-GCSc Inhibitors supports the development of experimental models to dissect the complex interactions between glutathione and various cellular processes, enhancing our understanding of cellular regulation and adaptation. View detailed information on our available gamma-GCSc Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-Buthionine sulfoximine

83730-53-4sc-200824
sc-200824A
sc-200824B
sc-200824C
500 mg
1 g
5 g
10 g
$286.00
$442.00
$1532.00
$2975.00
26
(1)

L-Buthionine sulfoximine functions as a potent inhibitor of gamma-glutamylcysteine synthetase, effectively disrupting the synthesis of glutathione. Its unique structure allows for specific interactions with the enzyme's active site, leading to altered reaction kinetics and a significant reduction in glutathione levels. This compound exhibits a high affinity for the enzyme, resulting in a sustained inhibitory effect that can influence oxidative stress responses and cellular redox balance.

D,L-Buthionine-(S,R)-sulfoximine

5072-26-4sc-207492
1 g
$270.00
1
(0)

D,L-Buthionine-(S,R)-sulfoximine acts as a selective inhibitor of gamma-glutamylcysteine synthetase, characterized by its ability to form stable complexes with the enzyme. This interaction modifies the enzyme's conformation, impacting substrate binding and catalytic efficiency. The compound's stereochemistry contributes to its specificity, allowing for nuanced modulation of cellular thiol levels and influencing metabolic pathways related to oxidative stress and detoxification processes.