GADD 34 Antibodies

Santa Cruz Biotechnology delivers a wide array of GADD 34 monoclonal antibodies for research focused on understanding cellular stress responses. GADD 34 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GADD 34, or Growth Arrest and DNA Damage-inducible protein 34, plays a significant role in cellular stress responses, particularly in the regulation of protein synthesis during stress conditions. GADD 34 is involved in the dephosphorylation of eIF2α, a key factor in the translation initiation process, thereby influencing cell survival and apoptosis. Understanding GADD 34 function is essential for elucidating mechanisms of cellular response to stress and its implications in various diseases. Research has shown that GADD 34 expression increases during cellular stress conditions, making it an important marker for studying stress response pathways. GADD 34 has been linked to various cellular processes including endoplasmic reticulum stress response and recovery from protein synthesis inhibition. Recent studies have highlighted GADD 34's potential role in neurodegenerative disorders and cancer development. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of cellular stress responses and their impact on human health.