Date published: 2026-1-9

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GABAA R α 6 Activators

Santa Cruz Biotechnology now offers a broad range of GABA A Rα6 Activators for use in various applications. GABA A receptors containing the α6 subunit are primarily found in the cerebellum, where they play a crucial role in regulating inhibitory neurotransmission, particularly in the modulation of motor control and coordination. These receptors are essential for maintaining the balance between excitatory and inhibitory signals in the nervous system, contributing to the fine-tuning of motor functions and the prevention of excessive neuronal excitability. GABA A Rα6 Activators are vital tools in scientific research, allowing researchers to selectively enhance the activity of these receptor subtypes and explore their specific roles in cerebellar function and overall neural processes. By activating GABA A Rα6, scientists can investigate the effects on motor coordination, synaptic inhibition, and neural circuitry, providing valuable insights into the underlying mechanisms of motor control and cerebellar function. These activators are widely used in electrophysiological studies, behavioral research, and pharmacological experiments to understand how modulation of GABA A Rα6 influences motor behavior and neural plasticity. Additionally, GABA A Rα6 Activators are valuable for research aimed at exploring the potential implications of targeting these receptors to address motor dysfunction and other neurological conditions. The availability of these activators has significantly advanced research in neurobiology and motor control, offering essential tools for dissecting the complex dynamics of inhibitory neurotransmission in the central nervous system. View detailed information on our available GABA A Rα6 Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

RO 15-4513

91917-65-6sc-203683
10 mg
$415.00
(0)

RO 15-4513 acts as a potent allosteric modulator at GABAA receptors, particularly those containing the alpha-6 subunit. Its unique binding dynamics facilitate enhanced receptor sensitivity to GABA, promoting a nuanced regulatory effect on inhibitory neurotransmission. The compound's stereochemistry contributes to its selective interaction with specific receptor conformations, influencing downstream signaling pathways. Additionally, its lipophilicity aids in membrane permeability, impacting its bioavailability and interaction with neuronal circuits.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc ions can modulate GABA(A) receptor activity, potentially enhancing inhibition.