Date published: 2025-11-5

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GABA Metabolism and Transport

Santa Cruz Biotechnology now offers a broad range of GABA metabolism and transport products for use in various applications. GABA (gamma-aminobutyric acid) is a critical neurotransmitter in the central nervous system, primarily responsible for inhibitory signaling. Understanding GABA metabolism and transport is vital in neuroscience research as it provides insights into how inhibitory signals are regulated within the brain. Researchers utilize GABA metabolism and transport products to study the enzymatic pathways involved in the synthesis and degradation of GABA, such as the roles of glutamate decarboxylase (GAD) and GABA transaminase. These products also help in investigating the function and regulation of GABA transporters, which are essential for maintaining appropriate GABA levels in synaptic and extrasynaptic spaces. By examining GABAergic signaling, scientists can explore the mechanisms underlying various neurological and psychiatric conditions, including anxiety, epilepsy, and sleep disorders. Additionally, GABA metabolism and transport products are used in the development of experimental models to study the effects of genetic modifications and pharmacological agents on GABAergic systems. By providing a comprehensive selection of high-quality GABA metabolism and transport products, Santa Cruz Biotechnology supports cutting-edge research in neurobiology, enabling scientists to achieve precise and reproducible results. These products facilitate a deeper understanding of GABAergic function and regulation, driving advancements in the field of neuroscience. View detailed information on our available GABA metabolism and transport products by clicking on the product name.

Items 61 to 70 of 87 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

β-Alanine

107-95-9sc-364682
sc-364682A
25 g
500 g
$31.00
$96.00
(0)

β-Alanine plays a significant role in GABA metabolism and transport, primarily through its involvement in the synthesis of carnosine, which modulates GABAergic activity. Its unique ability to interact with GABA transaminase influences the enzymatic conversion of GABA, impacting neurotransmitter levels. Additionally, β-Alanine's presence can affect the affinity and kinetics of GABA transporters, potentially altering the dynamics of GABA reuptake and availability in the synaptic cleft.

21-Acetoxypregnenolone

566-78-9sc-231272
sc-231272A
1 g
25 g
$52.00
$1102.00
(0)

21-Acetoxypregnenolone is a steroid compound that influences GABA metabolism and transport by modulating the activity of GABA receptors. Its structural features allow it to interact with specific binding sites, potentially altering receptor conformation and signaling pathways. This compound may also affect the enzymatic activity of GABA transaminase, thereby influencing the synthesis and degradation of GABA. Its unique interactions can lead to variations in GABAergic neurotransmission dynamics.

16α,17α-Epoxypregnenolone

974-23-2sc-223173
sc-223173A
5 g
10 g
$45.00
$83.00
(0)

16α,17α-Epoxypregnenolone is a steroidal compound that plays a role in GABA metabolism and transport through its unique epoxide structure, which facilitates specific interactions with GABAergic enzymes. This compound may enhance the affinity of GABA for its receptors, potentially influencing downstream signaling cascades. Additionally, it can modulate the activity of transport proteins, affecting GABA uptake and release, thereby impacting overall neurotransmitter balance.

SCS

3232-36-8sc-203375
50 mg
$105.00
(0)

SCS is a chemical that plays a significant role in GABA metabolism and transport by engaging with specific receptors and transport proteins. Its unique molecular structure allows for selective interactions that can modulate the activity of GABAergic pathways. By influencing the conformational states of transporters, SCS can affect the uptake and release of GABA, thereby impacting the overall balance of inhibitory signaling in neural circuits. This dynamic interaction highlights its potential to alter synaptic efficacy.

16,17-Epoxy-21-acetoxypregnenolone

28444-97-5sc-224977
1 g
$68.00
(0)

16,17-Epoxy-21-acetoxypregnenolone plays a distinctive role in GABA metabolism and transport by engaging in specific interactions with GABAergic systems. Its epoxy group introduces unique steric effects, influencing the conformational dynamics of GABA transporters. This compound may alter the transport kinetics, affecting the rate of GABA reuptake and thereby modulating synaptic availability. Additionally, its acetoxy moiety can enhance lipophilicity, impacting membrane permeability and distribution within neural tissues.

17α-Hydroxypregnenolone 3-acetate

41906-06-3sc-224980
5 g
$175.00
(0)

17α-Hydroxypregnenolone 3-acetate exhibits unique characteristics in GABA metabolism and transport through its structural features. The presence of the hydroxyl group at the 17α position facilitates hydrogen bonding with GABA receptors, potentially influencing receptor activation and signaling pathways. Its acetate group enhances hydrophobic interactions, which may affect the compound's affinity for lipid membranes, thereby altering the dynamics of GABA transport and synaptic modulation.

CGP 13501

56189-68-5sc-203542
sc-203542A
10 mg
50 mg
$161.00
$645.00
1
(0)

CGP 13501 plays a distinctive role in GABA metabolism and transport, characterized by its ability to modulate GABAergic signaling. Its structural configuration allows for specific interactions with GABA transporters, potentially influencing their kinetics and substrate affinity. The compound's unique electronic properties may enhance its interaction with membrane proteins, affecting the overall transport efficiency and influencing GABA homeostasis within neural circuits.

CGP 7930

57717-80-3sc-203543
sc-203543A
10 mg
50 mg
$155.00
$625.00
(0)

CGP 7930 is a notable compound in the realm of GABA metabolism and transport, distinguished by its selective binding affinity to GABA receptors. This interaction can alter the conformational dynamics of the receptors, impacting their activation and desensitization profiles. Additionally, CGP 7930 may influence the intracellular signaling pathways associated with GABAergic transmission, thereby affecting synaptic plasticity and neurotransmitter release mechanisms. Its unique structural features facilitate these complex molecular interactions.

S(+)-gamma-Vinyl-GABA

74046-07-4sc-222279
sc-222279A
sc-222279B
sc-222279C
sc-222279D
5 mg
10 mg
50 mg
100 mg
250 mg
$454.00
$719.00
$1722.00
$3065.00
$5105.00
(0)

S(+)-gamma-Vinyl-GABA is a unique compound that plays a significant role in GABA metabolism and transport by acting as a potent inhibitor of GABA transaminase. This inhibition leads to increased levels of GABA in the synaptic cleft, enhancing neurotransmission. Its distinct molecular structure allows for specific interactions with the enzyme, influencing reaction kinetics and altering metabolic pathways. The compound's stereochemistry contributes to its selectivity and efficacy in modulating GABAergic activity.

ZK 93423 hydrochloride

83910-44-5sc-204422
sc-204422A
10 mg
50 mg
$306.00
$969.00
(0)

ZK 93423 hydrochloride is a distinctive compound that influences GABA metabolism and transport through its interaction with GABA transporters. It exhibits a high affinity for these transporters, modulating their activity and affecting GABA reuptake dynamics. The compound's unique structural features facilitate specific binding interactions, altering the kinetics of GABA transport. This modulation can lead to significant changes in GABAergic signaling pathways, impacting overall neurotransmitter balance.