Date published: 2025-10-16

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CGP 13501 (CAS 56189-68-5)

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Alternate Names:
3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal
Application:
CGP 13501 is a positive allosteric modulator at GABAB receptors
CAS Number:
56189-68-5
Molecular Weight:
290.44
Molecular Formula:
C19H30O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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CGP 13501 is a positive allosteric modulator at GABAB receptors, potentiating the effects of GABA at this receptor type.


CGP 13501 (CAS 56189-68-5) References

  1. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.  |  Urwyler, S., et al. 2001. Mol Pharmacol. 60: 963-71. PMID: 11641424
  2. Identification of thyroid hormone receptor active compounds using a quantitative high-throughput screening platform.  |  Freitas, J., et al. 2014. Curr Chem Genom Transl Med. 8: 36-46. PMID: 24772387
  3. Androgen receptor antagonists compromise T cell response against prostate cancer leading to early tumor relapse.  |  Pu, Y., et al. 2016. Sci Transl Med. 8: 333ra47. PMID: 27053771
  4. Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish.  |  Bugel, SM. and Tanguay, RL. 2018. Toxicol Appl Pharmacol. 344: 23-34. PMID: 29499247
  5. Construction of a Fluorescent Screening System of Allosteric Modulators for the GABAA Receptor Using a Turn-On Probe.  |  Sakamoto, S., et al. 2019. ACS Cent Sci. 5: 1541-1553. PMID: 31572781

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CGP 13501, 10 mg

sc-203542
10 mg
$161.00

CGP 13501, 50 mg

sc-203542A
50 mg
$645.00