Date published: 2026-4-3

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FucT Substrates

Santa Cruz Biotechnology now offers a broad range of FucT Substrates for use in various applications. FucT Substrates are specifically designed compounds metabolized by fucosyltransferases (FucT), a family of enzymes that catalyze the transfer of fucose from GDP-fucose to various acceptor molecules, including glycoproteins and glycolipids. These substrates are vital for scientific research into the processes of fucosylation, an essential post-translational modification that impacts cell-cell communication, adhesion, and signaling. Researchers utilize FucT Substrates to study the enzymatic activity, specificity, and regulatory mechanisms of different fucosyltransferases, thereby gaining insights into how fucosylation affects various biological processes. These substrates enable the detailed mapping of glycan structures and the pathways involved in their synthesis and modification, providing a clearer understanding of the functional roles of fucosylation in cellular metabolism. In addition, FucT Substrates are used in the development of assays to measure the activity of fucosyltransferases, allowing for high-throughput screening and detailed kinetic studies. The use of these substrates in structural biology helps elucidate the three-dimensional configurations of fucosylated molecules and their interactions with other cellular components, revealing critical information about their functional sites and domains. This comprehensive understanding is fundamental for advancing research in cell biology, biochemistry, and glycomics. By facilitating precise control and observation of fucosylation processes, FucT Substrates are indispensable tools for researchers aiming to uncover the complexities of glycan biology and the regulatory networks that maintain cellular homeostasis. View detailed information on our available FucT Substrates by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Acetyl-D-lactosamine

32181-59-2sc-281053
5 mg
$59.00
(1)

N-Acetyl-D-lactosamine serves as a substrate for fucosyltransferases, playing a crucial role in glycosylation pathways. Its structural features allow for specific interactions with lectins, influencing cell-cell recognition and signaling. The compound's acetyl group enhances solubility and stability, while its unique stereochemistry promotes selective enzymatic modifications. Kinetics studies reveal its rapid incorporation into glycan structures, impacting cellular processes and interactions.

Guanosine 5′-diphospho-β-L-fucose sodium salt

15839-70-0sc-221696
sc-221696A
1 mg
2 mg
$214.00
$362.00
1
(0)

Guanosine 5'-diphospho-β-L-fucose sodium salt acts as a critical donor substrate for fucosyltransferases, facilitating the transfer of fucose residues in glycosylation reactions. Its unique β-linkage enables specific binding to target glycoproteins, influencing cellular adhesion and communication. The compound's diphosphate moiety enhances its reactivity, promoting efficient enzymatic catalysis. Kinetic analyses demonstrate its role in modulating glycan diversity, impacting various biological pathways.