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Guanosine 5′-diphospho-β-L-fucose sodium salt (CAS 15839-70-0)

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Application:
Guanosine 5′-diphospho-β-L-fucose sodium salt is a substrate for fucosyltransferase
CAS Number:
15839-70-0
Purity:
≥85%
Molecular Weight:
633.31
Molecular Formula:
C16H23N5O15P2•Na2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Guanosine 5′-diphospho-β-L-fucose sodium salt is a substrate for FucT (fucosyltransferase). Guanosine 5′-diphospho-β-L-fucose sodium salt (GDP-β-L-Fuc) is a naturally occurring carbohydrate with a significant presence in the cell walls of plants and bacteria. Guanosine 5′-diphospho-β-L-fucose sodium salt assumes a pivotal role in the biosynthesis pathways of glycoproteins and glycolipids, ensuring proper cellular function. Its indispensability extends to serving as a critical intermediate in the synthesis of polysaccharides, including those forming bacterial and fungal cell walls. Moreover, Guanosine 5′-diphospho-β-L-fucose sodium salt actively participates in the biosynthesis of vital polysaccharides such as N-acetylglucosamine, chitin, and heparan sulfate. The compound′s involvement is also evident in its contribution to glycoprotein and glycolipid biosynthesis, regulation of cell adhesion, modulation of cell signaling pathways, and influence on gene expression.


Guanosine 5′-diphospho-β-L-fucose sodium salt (CAS 15839-70-0) References

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  7. Chemo-Enzymatic Synthesis of (13)C Labeled Complex N-Glycans As Internal Standards for the Absolute Glycan Quantification by Mass Spectrometry.  |  Echeverria, B., et al. 2015. Anal Chem. 87: 11460-7. PMID: 26482441
  8. Divergent Chemoenzymatic Synthesis of Asymmetrical-Core-Fucosylated and Core-Unmodified N-Glycans.  |  Li, T., et al. 2016. Chemistry. 22: 18742-18746. PMID: 27798819
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  12. An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei.  |  Bandini, G., et al. 2021. Elife. 10: PMID: 34410224
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guanosine 5′-diphospho-β-L-fucose sodium salt, 1 mg

sc-221696
1 mg
$214.00

Guanosine 5′-diphospho-β-L-fucose sodium salt, 2 mg

sc-221696A
2 mg
$362.00