Forssman antigen inhibitors are chemical compounds that specifically target and inhibit the Forssman antigen, a glycolipid found on the surface of certain cells. The Forssman antigen is part of the Forssman glycolipid family, which is known for its role in cellular recognition and adhesion. This antigen, a heterophilic antigen, can be found in a variety of species, but its expression in humans is generally low or absent. The inhibitors designed to target the Forssman antigen interact with specific molecular components of the glycolipid, potentially disrupting its structural and functional properties on the cell membrane. These inhibitors are commonly studied in biochemical and cellular research, especially when investigating the antigen's role in intercellular interactions, immunological responses, or membrane dynamics.
Structurally, Forssman antigen inhibitors often mimic the configuration of carbohydrates or lipids, allowing them to bind selectively to the antigen's binding sites. By doing so, these inhibitors can affect processes like cell signaling and adhesion that are mediated by the antigen. Such inhibitors are valuable tools in research aimed at understanding the fundamental biology of cell membranes, particularly in relation to glycolipid-mediated cellular processes. Their specificity to the Forssman antigen makes them useful in dissecting the pathways and mechanisms associated with glycolipid function, providing insights into the complex interactions within the cellular environment. As research tools, Forssman antigen inhibitors contribute to the study of molecular and cellular biology, helping to clarify the functions of the Forssman glycolipid family across different organisms.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $41.00 $53.00 | 3 | |
Phenylbutyrate is a histone deacetylase inhibitor that can affect gene expression, potentially influencing glycolipid biosynthesis. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid influences cell differentiation and gene expression, which could include genes related to glycolipid synthesis. | ||||||
Fumonisin B1 | 116355-83-0 | sc-201395 sc-201395A | 1 mg 5 mg | $117.00 $469.00 | 18 | |
Fumonisin B1 inhibits ceramide synthase, a key enzyme in sphingolipid metabolism, potentially affecting glycolipid biosynthesis. | ||||||
Myriocin (ISP-1) | 35891-70-4 | sc-201397 | 10 mg | $106.00 | 8 | |
Myriocin is a potent inhibitor of serine palmitoyltransferase, the first enzyme in sphingolipid biosynthesis, which may influence glycolipid formation. | ||||||
Procyanidin B1 | 20315-25-7 | sc-228996 | 1 mg | $360.00 | ||
PDMP inhibits glucosylceramide synthase, affecting glycosphingolipid metabolism which includes glycolipids like the Forssman antigen. | ||||||
β-Cyclodextrin | 7585-39-9 | sc-204430 sc-204430A | 25 g 500 g | $59.00 $527.00 | 3 | |
β-Cyclodextrin can extract cholesterol from cell membranes, potentially affecting membrane composition and glycolipid organization. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $51.00 $292.00 | 3 | |
Progesterone can modulate gene expression and cellular metabolism, potentially influencing glycolipid biosynthesis. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can influence various signaling pathways and may indirectly affect glycolipid synthesis. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen, known for its anti-estrogen effects, can also impact lipid metabolism, potentially influencing glycolipid biosynthesis. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate, an antifolate, can influence cellular proliferation and metabolism, potentially affecting glycolipid synthesis. |