Date published: 2025-10-10

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Forssman Antigen Inhibitors

Forssman antigen inhibitors are chemical compounds that specifically target and inhibit the Forssman antigen, a glycolipid found on the surface of certain cells. The Forssman antigen is part of the Forssman glycolipid family, which is known for its role in cellular recognition and adhesion. This antigen, a heterophilic antigen, can be found in a variety of species, but its expression in humans is generally low or absent. The inhibitors designed to target the Forssman antigen interact with specific molecular components of the glycolipid, potentially disrupting its structural and functional properties on the cell membrane. These inhibitors are commonly studied in biochemical and cellular research, especially when investigating the antigen's role in intercellular interactions, immunological responses, or membrane dynamics.

Structurally, Forssman antigen inhibitors often mimic the configuration of carbohydrates or lipids, allowing them to bind selectively to the antigen's binding sites. By doing so, these inhibitors can affect processes like cell signaling and adhesion that are mediated by the antigen. Such inhibitors are valuable tools in research aimed at understanding the fundamental biology of cell membranes, particularly in relation to glycolipid-mediated cellular processes. Their specificity to the Forssman antigen makes them useful in dissecting the pathways and mechanisms associated with glycolipid function, providing insights into the complex interactions within the cellular environment. As research tools, Forssman antigen inhibitors contribute to the study of molecular and cellular biology, helping to clarify the functions of the Forssman glycolipid family across different organisms.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

6-Thioguanine

154-42-7sc-205587
sc-205587A
250 mg
500 mg
$41.00
$53.00
3
(1)

Phenylbutyrate is a histone deacetylase inhibitor that can affect gene expression, potentially influencing glycolipid biosynthesis.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic Acid influences cell differentiation and gene expression, which could include genes related to glycolipid synthesis.

Fumonisin B1

116355-83-0sc-201395
sc-201395A
1 mg
5 mg
$117.00
$469.00
18
(1)

Fumonisin B1 inhibits ceramide synthase, a key enzyme in sphingolipid metabolism, potentially affecting glycolipid biosynthesis.

Myriocin (ISP-1)

35891-70-4sc-201397
10 mg
$106.00
8
(2)

Myriocin is a potent inhibitor of serine palmitoyltransferase, the first enzyme in sphingolipid biosynthesis, which may influence glycolipid formation.

Procyanidin B1

20315-25-7sc-228996
1 mg
$360.00
(0)

PDMP inhibits glucosylceramide synthase, affecting glycosphingolipid metabolism which includes glycolipids like the Forssman antigen.

β-Cyclodextrin

7585-39-9sc-204430
sc-204430A
25 g
500 g
$59.00
$527.00
3
(1)

β-Cyclodextrin can extract cholesterol from cell membranes, potentially affecting membrane composition and glycolipid organization.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$51.00
$292.00
3
(1)

Progesterone can modulate gene expression and cellular metabolism, potentially influencing glycolipid biosynthesis.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein, a tyrosine kinase inhibitor, can influence various signaling pathways and may indirectly affect glycolipid synthesis.

Tamoxifen

10540-29-1sc-208414
2.5 g
$256.00
18
(2)

Tamoxifen, known for its anti-estrogen effects, can also impact lipid metabolism, potentially influencing glycolipid biosynthesis.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate, an antifolate, can influence cellular proliferation and metabolism, potentially affecting glycolipid synthesis.