6-Thioguanine CAS: 154-42-7
MF: C5H5N5S
MW: 167.19
An immunosuppressive, anti-neoplastic, and anti-cancer.

6-Thioguanine (CAS 154-42-7)

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Alternate Names: 2-Amino-6-purinethiol
Application 6-Thioguanine is an immunosuppressive, anti-neoplastic, and anti-cancer
CAS 등록번호: 154-42-7
분자량: 167.19
분자식: C5H5N5S
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.


References

Karran P. Br Med Bull 79-80: 153-70 (2006). Sartorelli AC, Booth BA. Cancer Res. 25: 1393-40 (1965).

Physical State :
Solid
에서 유래된 :
Synthetic
용해도 :
Soluble in DMSO (100 mM).
저장 :
Store at room temperature
녹는점 :
>300° C (lit.)(dec.)
비등점 :
~460.7° C at 760 mmHg (Predicted)
밀도 :
~2.1 g/cm3 (Predicted)
굴절률 :
n20D 2.07 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
UP0740000
PubChem CID :
Merck Index :
14: 9337
MDL Number :
MFCD00233553
EC Number :
205-827-2
Beilstein Registry :
157765
SMILES :
C1=NC2=C(N1)C(=S)N=C(N2)N

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분석증명서

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PMID: # 33668818  Riemschneider, S.|Hoffmann, M.|Slanina, U.|Weber, K.|Hauschildt, S.|Lehmann, J.| et al. 2021. Int J Environ Res Public Health. 18:

PMID: # 29192559  Hoffmann, M.|Schwertassek, U.|Seydel, A.|Weber, K.|Falk, W.|Hauschildt, S.|Lehmann, J.| et al. 2018. Lab Anim. 52: 240-252.

PMID: # 29079781  Hoffmann, M.|Schwertassek, U.|Seydel, A.|Weber, K.|Hauschildt, S.|Lehmann, J.| et al. 2017. Sci Rep. 7: 14214.

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