Date published: 2025-10-30

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FLJ10357 Inhibitors

FLJ10357 inhibitors represent a class of compounds that target the activity of the FLJ10357 gene product, a protein implicated in several intracellular processes. The FLJ10357 gene, also known as CCDC50, encodes a protein associated with various signaling pathways and cellular functions, including protein-protein interactions. Inhibition of the FLJ10357 protein can disrupt its normal role in these pathways, which may affect cellular homeostasis, protein folding, or interactions with other molecular complexes. The inhibitors within this class are often characterized by their ability to bind to specific sites on the FLJ10357 protein, potentially leading to conformational changes that reduce or prevent the protein's functional activity. These interactions are essential to understanding how this gene's activity can be modulated and how it contributes to cellular signaling networks.

With FLJ10357 inhibitors, a wide range of molecular structures can be observed, reflecting the diversity of compounds that can interact with this target protein. Some inhibitors exhibit specificity towards FLJ10357 through non-covalent binding, forming stable yet reversible interactions with the target protein. Others may bind covalently, leading to a more permanent inhibition. These inhibitors are valuable tools in exploring the molecular biology of FLJ10357, aiding in the elucidation of its structural and functional roles within the cell. Further research into these inhibitors allows for a deeper understanding of protein regulation, folding, and the complex networks of intracellular communication in which FLJ10357 is involved. These insights are critical for advancing the field of molecular biology, particularly in the study of protein interactions and signaling mechanisms.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D binds to DNA, inhibiting RNA synthesis, which may lead to a reduction in the transcription of ARHGEF40 and other genes.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

MG-132 is a proteasome inhibitor that can affect protein stability. Inhibition of proteasomes may lead to reduced levels of ARHGEF40.

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$56.00
$212.00
$764.00
24
(1)

Nutlin-3 inhibits MDM2, stabilizing p53. Elevated p53 levels can alter gene expression patterns, potentially impacting ARHGEF40.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

TSA is an HDAC inhibitor that affects histone acetylation and can influence the chromatin environment, possibly affecting ARHGEF40.

Chromomycin A3

7059-24-7sc-200907
10 mg
$255.00
(1)

Similar to Actinomycin D, Actinomycin C1 inhibits RNA synthesis, which can lead to reduced transcription of ARHGEF40 and other genes.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

Doxorubicin is a DNA-damaging chemotherapy drug that can impact DNA transcription, potentially affecting ARHGEF40 expression.

2′-Deoxy-2′,2′-difluorocytidine

95058-81-4sc-275523
sc-275523A
1 g
5 g
$56.00
$128.00
(1)

Gemcitabine, a nucleoside analog, can interfere with DNA synthesis and repair, potentially affecting the transcription of ARHGEF40.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat is an HDAC inhibitor that alters histone acetylation patterns, potentially influencing the transcription of ARHGEF40.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$76.00
$216.00
101
(4)

Cisplatin is a DNA-damaging agent that can induce DNA damage responses, which may affect the transcription of ARHGEF40 and other genes.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Sirolimus is an mTOR inhibitor that can influence cellular signaling pathways, potentially affecting the expression of ARHGEF40.