FLJ10357 inhibitors represent a class of compounds that target the activity of the FLJ10357 gene product, a protein implicated in several intracellular processes. The FLJ10357 gene, also known as CCDC50, encodes a protein associated with various signaling pathways and cellular functions, including protein-protein interactions. Inhibition of the FLJ10357 protein can disrupt its normal role in these pathways, which may affect cellular homeostasis, protein folding, or interactions with other molecular complexes. The inhibitors within this class are often characterized by their ability to bind to specific sites on the FLJ10357 protein, potentially leading to conformational changes that reduce or prevent the protein's functional activity. These interactions are essential to understanding how this gene's activity can be modulated and how it contributes to cellular signaling networks.
With FLJ10357 inhibitors, a wide range of molecular structures can be observed, reflecting the diversity of compounds that can interact with this target protein. Some inhibitors exhibit specificity towards FLJ10357 through non-covalent binding, forming stable yet reversible interactions with the target protein. Others may bind covalently, leading to a more permanent inhibition. These inhibitors are valuable tools in exploring the molecular biology of FLJ10357, aiding in the elucidation of its structural and functional roles within the cell. Further research into these inhibitors allows for a deeper understanding of protein regulation, folding, and the complex networks of intracellular communication in which FLJ10357 is involved. These insights are critical for advancing the field of molecular biology, particularly in the study of protein interactions and signaling mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA, inhibiting RNA synthesis, which may lead to a reduction in the transcription of ARHGEF40 and other genes. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG-132 is a proteasome inhibitor that can affect protein stability. Inhibition of proteasomes may lead to reduced levels of ARHGEF40. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 inhibits MDM2, stabilizing p53. Elevated p53 levels can alter gene expression patterns, potentially impacting ARHGEF40. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA is an HDAC inhibitor that affects histone acetylation and can influence the chromatin environment, possibly affecting ARHGEF40. | ||||||
Chromomycin A3 | 7059-24-7 | sc-200907 | 10 mg | $255.00 | ||
Similar to Actinomycin D, Actinomycin C1 inhibits RNA synthesis, which can lead to reduced transcription of ARHGEF40 and other genes. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin is a DNA-damaging chemotherapy drug that can impact DNA transcription, potentially affecting ARHGEF40 expression. | ||||||
2′-Deoxy-2′,2′-difluorocytidine | 95058-81-4 | sc-275523 sc-275523A | 1 g 5 g | $56.00 $128.00 | ||
Gemcitabine, a nucleoside analog, can interfere with DNA synthesis and repair, potentially affecting the transcription of ARHGEF40. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is an HDAC inhibitor that alters histone acetylation patterns, potentially influencing the transcription of ARHGEF40. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin is a DNA-damaging agent that can induce DNA damage responses, which may affect the transcription of ARHGEF40 and other genes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus is an mTOR inhibitor that can influence cellular signaling pathways, potentially affecting the expression of ARHGEF40. | ||||||