FAM83C Activators

Family with sequence similarity 83, member C (FAM83C), is a protein that, as its name suggests, belongs to the FAM83 protein family, characterized by a conserved domain of unknown function, DUF1669. FAM83C is believed to play a role in cellular processes such as proliferation and differentiation, and it has captured the interest of researchers due to its potential involvement in the pathology of certain types of cancer.The FAM83C protein is encoded by the FAM83C gene and has been identified as a potential oncogene in various studies. It has been observed to be overexpressed in certain carcinomas, which suggests that it might contribute to tumorigenesis, likely through the dysregulation of signaling pathways that control cell division and growth. The molecular mechanisms through which FAM83C exerts its effects, however, are not fully understood.

Research has indicated that FAM83C may interact with components of key signaling pathways, such as the PI3K/AKT/mTOR pathway, which is known for its role in regulating cell survival, protein synthesis, and metabolism. These interactions may lead to aberrant activation of the pathway, contributing to the uncontrolled cell growth characteristic of cancerous tissues.The specific function of the DUF1669 domain within FAM83C remains a mystery. It is possible that this domain mediates protein-protein interactions that are critical for the regulatory roles the protein might have in signaling cascades. Further research into the structure and binding partners of FAM83C could provide insights into the domain's function and the protein's overall role in cellular biology.