FAM83C Antibody (C-11): sc-390398

FAM83C Antibody (C-11) is a mouse monoclonal IgM antibody that detects FAM83C of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-FAM83C antibody (C-11) is available as the non-conjugated form. FAM83C plays a crucial role in cellular signaling pathways, particularly in regulating the RAS signaling cascade, which is vital for cell growth and differentiation. Dysregulation of this pathway can lead to various cancers, making FAM83C an important protein for understanding tumorigenesis and potential therapeutic targets. FAM83C is located on chromosome 20, a region associated with several genetic disorders, including amyotrophic lateral sclerosis and Alagille syndrome, highlighting FAM83C′s significance in both normal physiology and disease states. FAM83C has been provisionally designated pending further characterization, and ongoing research continues to explore FAM83C′s interactions with other proteins and potential implications in cancer biology.

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FAM83C Antibody (C-11) References:

1. Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?  |  Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
2. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.  |  Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
3. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
4. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
5. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
6. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
7. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
8. Cellular pathways leading to neuronal dysfunction and degeneration.  |  Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
9. The prion diseases.  |  Prusiner, SB. 1998. Brain Pathol. 8: 499-513. PMID: 9669700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAM83C Antibody (C-11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FAM83C Antibody (C-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAM83C Antibody (C-11) Specifications

Alternate Product Name: FAM83C

Product Clone Name: C-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 631-669

Epitope Target: FAM83C

Epitope Species: human

Product Reactivity/Detection: FAM83C

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FAM83C Antibody (C-11): P: Blocking Peptide