Date published: 2026-5-30

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FAM58A Inhibitors

FAM58A inhibitors are a category of chemicals designed to specifically target and inhibit the function of the FAM58A gene product. The FAM58A gene is known for its role in cellular processes, and its product is a protein involved in various intracellular signaling pathways and cellular functions. The inhibitors targeting this protein are characterized by their ability to interact with the FAM58A protein, thereby modulating its activity or stability within the cell. This modulation can affect several cellular processes, given the protein's involvement in critical cellular functions. The chemical structures of these inhibitors are diverse, reflecting the different mechanisms through which they can achieve inhibition. Some may directly bind to the FAM58A protein, altering its ability to interact with other cellular components, while others might interfere with the protein's expression or post-translational modifications. The action mechanisms of FAM58A inhibitors are varied and sophisticated, encompassing multiple types of molecular interactions. Some of these inhibitors function by binding directly to the FAM58A protein, thereby inhibiting its normal activity or interaction with other cellular proteins. This direct interaction can result in the alteration of the protein's conformation, leading to a decrease in its functional efficacy. Other inhibitors might operate indirectly, targeting the regulatory pathways that control the expression, processing, or stability of the FAM58A protein. These can include inhibitors that affect the transcription or translation of the FAM58A gene, as well as those that influence post-translational modifications critical for the protein's function. The development and utilization of FAM58A inhibitors require an in-depth understanding of the protein's role in cellular processes, as well as knowledge about the specific molecular interactions and pathways involved. This class of inhibitors is particularly significant in the field of molecular biology and biochemistry, where they are used as tools to elucidate the function of FAM58A in cellular processes and to explore the complex networks of protein-protein interactions within the cell.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

Another histone deacetylase inhibitor that can change chromatin dynamics, potentially impacting FAM58A gene transcription.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Affects the methylation state of DNA, potentially influencing the expression of genes like FAM58A.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

By binding to GC-rich DNA sequences, Mithramycin A can inhibit transcription factors, potentially affecting FAM58A expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Intercalates into DNA, inhibiting RNA synthesis. This could potentially decrease FAM58A transcription.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibits RNA polymerase II, impacting mRNA transcription and potentially decreasing FAM58A expression.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

Inhibits bromodomain-containing proteins, influencing gene expression. Its broad effects might impact FAM58A transcription.

Pladienolide B

445493-23-2sc-391691
sc-391691B
sc-391691A
sc-391691C
sc-391691D
sc-391691E
0.5 mg
10 mg
20 mg
50 mg
100 mg
5 mg
$299.00
$5699.00
$11099.00
$25500.00
$66300.00
$2875.00
63
(2)

Inhibits the spliceosome, potentially affecting the maturation of FAM58A mRNA.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

By inhibiting NF-κB activation, this compound might indirectly affect transcriptional regulation, including that of FAM58A.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

As a proteasome inhibitor, MG-132 might impact protein turnover, potentially influencing FAM58A stability or expression.