Family with sequence similarity 167 member A (FAM167A), also known by its gene symbol FAM167A, is a relatively lesser-characterized protein that belongs to a family of proteins with conserved sequence motifs. FAM167A is encoded by the FAM167A gene located on chromosome 3 in humans. The biological functions of FAM167A are not fully elucidated; however, it is thought to be involved in various cellular processes due to its widespread expression in different tissues.
Alterations in the expression or function of FAM167A have been associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), indicating a possible role in the regulation of the immune system. Additionally, genetic studies have identified single nucleotide polymorphisms (SNPs) within the FAM167A gene that are linked to increased susceptibility to SLE, suggesting that FAM167A's function could be crucial for maintaining immune homeostasis.Although the exact molecular mechanisms of FAM167A action remain to be fully determined, ongoing research continues to explore its potential interactions and effects on cellular signaling pathways. Understanding the role of FAM167A in health and disease is of interest to the scientific community, as it may shed light on novel pathways affecting immune function.
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