Date published: 2026-4-1

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EVI2A Inhibitors

EVI2A inhibitors represent a chemical class that targets the EVI2A gene, which encodes a membrane protein expressed in various cell types. EVI2A is notably involved in cellular signaling pathways and may influence gene expression, cell differentiation, and proliferation. Inhibitors targeting EVI2A are designed to interfere with the protein's ability to participate in these molecular pathways. Structurally, EVI2A inhibitors often contain binding domains that specifically interact with the protein or its associated molecular partners, effectively modulating its functional activity. These compounds may operate by directly binding to the EVI2A protein or by affecting upstream or downstream elements of its signaling network, thus altering the dynamic cellular processes in which EVI2A plays a role. Given the role of EVI2A in various cellular mechanisms, inhibitors of this protein have the potential to serve as valuable tools in research focused on understanding gene regulation and protein interactions.

From a biochemical perspective, EVI2A inhibitors are an important asset for probing the mechanisms underlying the function of the EVI2A protein and its related pathways. By modulating the activity of EVI2A, researchers can gain insight into how this protein influences processes such as signal transduction, transcriptional regulation, and cellular communication. Furthermore, these inhibitors can be utilized in experiments to dissect the molecular context in which EVI2A functions, providing a platform for exploring the broader cellular networks involved. The design and optimization of EVI2A inhibitors rely heavily on structural biology, molecular docking studies, and other advanced techniques to enhance their specificity and binding affinity, making them highly effective tools in molecular biology research.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

A potent kinase inhibitor that can affect multiple signaling pathways potentially involved with EVI2A.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor that can alter AKT signaling, possibly affecting pathways associated with EVI2A.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor which can change gene expression patterns, potentially altering EVI2A expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

An inhibitor of histone deacetylase which can affect chromatin structure and gene expression, potentially influencing EVI2A.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that can affect cell growth and proliferation pathways, potentially influencing EVI2A activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Another MEK inhibitor that can block the MAPK/ERK pathway, potentially affecting EVI2A-related signaling.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

A JNK inhibitor which can modulate stress response pathways, potentially impacting EVI2A signaling.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

A p38 MAPK inhibitor that can affect inflammatory response pathways, potentially influencing EVI2A.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

A PI3K inhibitor like LY294002 that may affect pathways associated with EVI2A.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

A SERCA pump inhibitor that can disrupt calcium homeostasis, potentially impacting EVI2A-related signaling.