ERVK6 Inhibitors constitute a specialized class of chemical compounds designed to selectively impede the activity of the ERVK6 enzyme. ERVK6, or Endogenous Retrovirus Group K Member 6, belongs to the family of endogenous retroviruses, which are remnants of ancient viral infections that have integrated into the human genome. Specifically, ERVK6 is a retroviral gene that has been preserved through evolution and retained within the genomic DNA of humans. The development of inhibitors targeting ERVK6 is crucial for scientific investigations, offering researchers specific tools to unravel the molecular functions and regulatory roles associated with this particular retroviral gene.
The synthesis and optimization of ERVK6 inhibitors necessitate a comprehensive understanding of the enzyme's structural characteristics and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of ERVK6 and interfere with its normal activities. By employing ERVK6 inhibitors in experimental settings, researchers can explore the consequences of gene product inhibition on cellular processes, shedding light on the specific molecular pathways influenced by ERVK6. The study of ERVK6 inhibitors contributes to the broader exploration of retroviral elements within the human genome, providing insights into the intricate molecular machinery that shapes genomic evolution and understanding the roles played by endogenous retroviruses in cellular biology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA, inhibiting transcription and preventing the synthesis of ERVK6 mRNA. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide disrupts protein synthesis, leading to a reduction in ERVK6 expression by inhibiting translation. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin induces premature termination of protein synthesis, impacting translation and lowering ERVK6 levels. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin inhibits bacterial RNA polymerase, indirectly suppressing ERVK6 expression by interfering with transcription. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin hinders protein synthesis by blocking peptidyl transferase activity, leading to reduced ERVK6 synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin interferes with mRNA synthesis, impacting transcription and contributing to the downregulation of ERVK6. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, indirectly affecting ERVK6 expression by disrupting purine synthesis. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $360.00 $475.00 | 20 | |
Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing ERVK6 levels. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil interferes with RNA synthesis, affecting the expression of ERVK6 by disrupting the production of mRNA. |