Date published: 2026-4-29

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Elf-5 Inhibitors

Elf-5 inhibitors are a class of small molecules and compounds that play a crucial role in regulating the activity of the E74-like factor 5 (Elf-5) protein. Elf-5, a transcription factor, is an essential component of the ETS family of transcription factors, which are pivotal in controlling gene expression and thereby influencing various cellular processes. Elf-5 itself is primarily associated with the regulation of mammary gland development, embryogenesis, and tissue-specific gene expression. Inhibitors of Elf-5 are designed to modulate its activity, primarily by binding to specific regions on the Elf-5 protein or interfering with its downstream signaling pathways. By doing so, Elf-5 inhibitors can exert significant influence over cellular processes governed by Elf-5, making them a valuable tool for research into various biological phenomena. The development and utilization of Elf-5 inhibitors have opened up new avenues of research in the field of molecular biology and genetics. These inhibitors are instrumental in elucidating the precise mechanisms through which Elf-5 governs gene expression and cellular differentiation. Additionally, they are employed to explore the role of Elf-5 in both normal development and pathological conditions, helping researchers gain insights into the molecular underpinnings of diseases. Furthermore, Elf-5 inhibitors have the potential to be instrumental in the development of novel strategies for manipulating cellular processes, although their application in this context remains a subject of ongoing research. In essence, Elf-5 inhibitors represent a valuable tool for scientists seeking to understand the intricate regulatory networks within cells and their implications for development and disease.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pyrvinium Pamoate

3546-41-6sc-476920A
sc-476920
250 mg
500 mg
$228.00
$422.00
(0)

Inhibits ELF-5 through destabilization of its mRNA, reducing its expression and activity.

Tyrphostin AG 879

148741-30-4sc-3557
sc-3557A
5 mg
25 mg
$83.00
$328.00
4
(1)

Acts as a tyrosine kinase inhibitor, targeting the kinase activity required for ELF-5 function.

AZD-0156

1821428-35-6sc-507529
10 mg
$280.00
(0)

Blocks ELF-5 by inhibiting its phosphorylation and downstream signaling pathways.

CDC25 Phosphatase Inhibitor II, NSC 663284

383907-43-5sc-202987A
sc-202987
sc-202987B
sc-202987C
1 mg
5 mg
10 mg
25 mg
$51.00
$241.00
$357.00
$663.00
4
(1)

Disrupts ELF-5 DNA binding by interacting with its DNA binding domain.

Lck Inhibitor Inhibitor

213743-31-8sc-204052
1 mg
$362.00
5
(1)

Targets ELF-5 by inhibiting its interaction with co-factors, disrupting its transcriptional activity.

ETP-46464

1345675-02-6sc-497432
10 mg
$550.00
(0)

Inhibits ELF-5 expression by modulating its promoter region.

UNC0638

1255580-76-7sc-397012
10 mg
$315.00
(0)

Epigenetically represses ELF-5 transcription through histone modification.

GSK343

1346704-33-3sc-397025
sc-397025A
5 mg
25 mg
$151.00
$461.00
1
(0)

An EZH2 inhibitor that indirectly downregulates ELF-5 through epigenetic regulation.

9-[5-Deoxy-5-[[cis-3-[2-[6-(1,1-dimethylethyl)-1H-benzimidazol-2-yl]ethyl]cyclobutyl](1-methylethyl)amino]-β-D-ribofuranosyl]-9H-purin-6-amine

1380288-87-8sc-500607
50 mg
$13500.00
(0)

Targets ELF-5 by inhibiting DOT1L, an enzyme responsible for histone methylation at its promoter.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

Disrupts ELF-5 expression by inhibiting the BRD4 protein and its role in transcriptional regulation.