Date published: 2025-12-19

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EHBP1L1 Inhibitors

EHBP1L1 inhibitors represent a specialized category of chemical compounds designed to target and modulate the activity of EHBP1L1, which stands for Eps15 Homology (EH) Domain Binding Protein 1-Like 1. EHBP1L1 is a protein that plays essential roles in intracellular membrane trafficking and vesicle transport within cells. Specifically, it is known to interact with various proteins and membrane structures involved in endocytosis, a process by which cells internalize external substances and receptors. Inhibitors of EHBP1L1 are developed to interact with this specific protein, potentially influencing its interactions with binding partners, its subcellular localization, or its participation in cellular processes related to endocytosis and membrane dynamics.

Structurally, EHBP1L1 inhibitors are meticulously designed to engage specific regions or binding sites on the EHBP1L1 protein. This interaction can disrupt the normal functioning of EHBP1L1, potentially affecting its role in coordinating membrane trafficking events, endocytic processes, and vesicle transport within cells. The mechanisms by which EHBP1L1 inhibitors exert their effects can vary, but their primary purpose is to serve as valuable tools for researchers studying the roles of EHBP1L1 in various cellular contexts. Investigating the biochemical and functional aspects of EHBP1L1 and its modulation by inhibitors can contribute to a deeper understanding of intracellular membrane dynamics, endocytosis, and the broader field of molecular and cellular biology. Ultimately, such research can offer insights into the intricate molecular mechanisms that govern fundamental cellular functions and their potential regulation by EHBP1L1.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dynamin Inhibitor I, Dynasore

304448-55-3sc-202592
10 mg
$87.00
44
(2)

Dynasore is a non-competitive inhibitor of dynamin, which is involved in endocytosis. It could potentially affect EHBP1L1's role in endocytic trafficking.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$145.00
$442.00
64
(4)

This compound disrupts actin polymerization, which is crucial for cytoskeletal dynamics and can indirectly influence EHBP1L1.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

Nocodazole disrupts microtubule dynamics which can indirectly impact proteins involved in cytoskeletal dynamics, including EHBP1L1.

5-(N-Ethyl-N-isopropyl)-Amiloride

1154-25-2sc-202458
5 mg
$102.00
20
(1)

EIPA inhibits macropinocytosis, which is a form of endocytosis, potentially affecting EHBP1L1's function.

Dansylcadaverine

10121-91-2sc-214851
sc-214851A
sc-214851B
100 mg
250 mg
1 g
$51.00
$87.00
$235.00
4
(1)

This compound is used to inhibit autophagic lysosome reformation, which might have indirect effects on endocytic pathways involving EHBP1L1.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

By stabilizing microtubules, paclitaxel can alter cytoskeletal dynamics and could potentially influence EHBP1L1.

ML 141

71203-35-5sc-362768
sc-362768A
5 mg
25 mg
$134.00
$502.00
7
(1)

ML-141 is a selective Cdc42 GTPase inhibitor, affecting cytoskeletal organization, and can potentially impact EHBP1L1 indirectly.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$315.00
$1020.00
5
(0)

An Arp2/3 complex inhibitor, CK-666 affects actin polymerization, potentially influencing EHBP1L1's role in cytoskeletal dynamics.

SMIFH2

340316-62-3sc-507273
5 mg
$140.00
(0)

Inhibitor of formins which are involved in actin polymerization, potentially affecting EHBP1L1's function in cytoskeleton dynamics.

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$180.00
$299.00
59
(1)

This compound stabilizes actin filaments and affects cytoskeletal dynamics, possibly having an indirect effect on EHBP1L1.