EG626305 Activators
Scgb1b7, a member of the secretoglobin family, is predicted to possess steroid-binding activity and is active in the extracellular region. Despite the predicted function, the specific role and downstream effects of Scgb1b7 activation remain to be fully elucidated. The potential involvement in steroid binding suggests a role in hormonal regulation, yet the precise mechanisms and implications in cellular processes remain speculative. Activation of Scgb1b7 involves various chemicals influencing its expression and secretion into the extracellular milieu. Dexamethasone, a synthetic glucocorticoid, directly activates Scgb1b7 by binding to its predicted steroid-binding site, highlighting a potential role in hormonal responses. Indirect activation is achieved through modulators like Retinoic Acid, Forskolin, and Butyrate, which influence retinoid signaling, cAMP-dependent pathways, and histone deacetylases, respectively. These chemicals establish intricate connections between signaling pathways and the up-regulation of Scgb1b7, suggesting a complex regulatory network.
Despite the wealth of information on activation mechanisms, Scgb1b7's exact role in steroid binding and extracellular activity remains enigmatic. Further investigations into the specific pathways influenced by Scgb1b7 and its potential impact on hormonal regulation are crucial for a comprehensive understanding of its function in cellular processes. The intricate interplay between chemical activators and Scgb1b7 highlights the need for continued research to unravel the intricacies of this predicted steroid-binding protein.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone directly activates Scgb1b7 by binding to its predicted steroid-binding site. This interaction enhances Scgb1b7 expression and secretion into the extracellular region. Dexamethasone's role as a synthetic glucocorticoid establishes a direct mechanism for the activation of Scgb1b7, influencing steroid binding and extracellular activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid indirectly activates Scgb1b7 by modulating retinoid signaling. This activation enhances Scgb1b7 expression in the extracellular region. Retinoic Acid's influence on the retinoid pathway establishes an indirect mechanism for Scgb1b7 activation, connecting retinoid signaling to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates Scgb1b7 through adrenergic receptors, triggering downstream signaling pathways. This activation enhances Scgb1b7 expression in the extracellular region. Epinephrine's role in adrenergic signaling establishes a direct mechanism for Scgb1b7 activation, connecting sympathetic nervous system activation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid indirectly activates Scgb1b7 through histone deacetylase inhibition. This epigenetic modulation enhances Scgb1b7 expression in the extracellular region. Valproic Acid's role as an HDAC inhibitor establishes an indirect mechanism for Scgb1b7 activation, linking histone acetylation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
Norepinephrine activates Scgb1b7 through adrenergic receptors, initiating downstream signaling pathways. This activation enhances Scgb1b7 expression in the extracellular region. Norepinephrine's involvement in adrenergic signaling establishes a direct mechanism for Scgb1b7 activation, connecting sympathetic nervous system activation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyric acid indirectly activates Scgb1b7 by inhibiting histone deacetylases. This epigenetic modulation enhances Scgb1b7 expression in the extracellular region. Butyrate's role as an HDAC inhibitor establishes an indirect mechanism for Scgb1b7 activation, linking histone acetylation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
9-cis-Retinoic Acid indirectly activates Scgb1b7 by engaging retinoid signaling. This activation enhances Scgb1b7 expression in the extracellular region. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate indirectly activates Scgb1b7 through histone deacetylase inhibition. This epigenetic modulation enhances Scgb1b7 expression in the extracellular region. Sodium Butyrate's role as an HDAC inhibitor establishes an indirect mechanism for Scgb1b7 activation, linking histone acetylation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Adenosine 3',5'-cyclic monophosphate directly activates Scgb1b7 by modulating cAMP-dependent pathways, enhancing extracellular expression. Cyclic AMP's role as a secondary messenger establishes a direct mechanism for Scgb1b7 activation, connecting cAMP signaling to the up-regulation of Scgb1b7 and its potential steroid-binding activity in the extracellular milieu. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 indirectly activates Scgb1b7 by inhibiting the TGF-β/Smad signaling pathway. This inhibition enhances Scgb1b7 expression in the extracellular region. SB431542's impact on TGF-β/Smad signaling establishes an indirect mechanism for Scgb1b7 activation, connecting pathway modulation to the up-regulation of Scgb1b7 and its potential steroid-binding activity. | ||||||