The chemical class referred to as EG433632 Inhibitors encompasses a diverse group of compounds that can potentially inhibit EG433632 through various mechanisms. These inhibitors target different cellular pathways and processes associated with EG433632 activation. Forskolin, an activator of adenylate cyclase, may activate EG433632 indirectly by increasing cAMP levels, which can influence downstream pathways contributing to its activation.
Phorbol 12-myristate 13-acetate (PMA) and 8-Br-cAMP are activators that potentially influence EG433632 by stimulating protein kinase C (PKC) or mimicking the effects of cAMP, respectively. Sodium orthovanadate, a protein tyrosine phosphatase inhibitor, may activate EG433632 by preventing the dephosphorylation of tyrosine residues, positively influencing its activity. Retinoic acid, through its effects on gene expression, and dibutyryl cGMP, by mimicking cGMP intracellular effects, may also activate EG433632 indirectly.
GW5074, a Raf-1 inhibitor, may activate EG433632 by blocking the inhibitory effect of Raf-1. A23187, a calcium ionophore, may activate EG433632 by increasing intracellular calcium levels, triggering downstream signaling pathways. IBMX, a phosphodiesterase inhibitor, may activate EG433632 by preventing cAMP degradation, leading to increased cAMP levels and downstream activation. Prostaglandin E2 (PGE2) activates EG433632 by binding to its receptors and triggering intracellular signaling.
Trichostatin A, a histone deacetylase inhibitor, may activate EG433632 by influencing histone acetylation and gene expression. Betulinic acid, a natural compound, may activate EG433632 through diverse mechanisms affecting cellular processes. The intricate regulatory network of EG433632 and the variety of potential activators offer avenues for further exploration in understanding its functional roles in cellular processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA, a PKC activator, may activate EG433632 by stimulating protein kinase C (PKC). Activated PKC can modulate various cellular processes, potentially influencing EG433632 activity and leading to its activation. | ||||||
Rp-8-Br-cAMPS | 129735-00-8 | sc-3539A sc-3539 | 500 µg 1 mg | $194.00 $336.00 | 22 | |
8-Br-cAMP, a cell-permeable cAMP analog, can activate EG433632 indirectly by mimicking the intracellular effects of cAMP. This analog may stimulate downstream pathways, influencing EG433632 activity and contributing to its activation. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium orthovanadate, a protein tyrosine phosphatase inhibitor, can potentially activate EG433632 by inhibiting the dephosphorylation of tyrosine residues. Elevated tyrosine phosphorylation may positively influence EG433632 activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a vitamin A derivative, may activate EG433632 indirectly by modulating gene expression. The influence on gene expression could lead to changes in cellular processes that positively impact EG433632 activity and activation. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
GW5074, a Raf-1 inhibitor, can potentially activate EG433632 by blocking the inhibitory effect of Raf-1. Inhibition of Raf-1 could lead to the activation of downstream pathways positively influencing EG433632 activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187, a calcium ionophore, may activate EG433632 by increasing intracellular calcium levels. Elevated calcium levels can trigger various signaling pathways, potentially influencing EG433632 activity and contributing to its activation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX, a phosphodiesterase inhibitor, can potentially activate EG433632 by preventing cAMP degradation. Increased cAMP levels can activate downstream pathways that positively influence EG433632 activity, leading to its activation. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2), a prostaglandin analog, can activate EG433632 indirectly by binding to its receptors and triggering intracellular signaling. This activation may lead to downstream events positively influencing EG433632 activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, may activate EG433632 by influencing histone acetylation and gene expression. The modulation of gene expression could lead to changes in cellular processes that positively impact EG433632 activity. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Betulinic acid, a natural compound, may activate EG433632 by influencing various cellular processes. The specific mechanisms are diverse and could include modulation of gene expression, ion channels, or other signaling pathways positively affecting EG433632 activity. | ||||||