Dynactin 1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
HPI-4 | 302803-72-1 | sc-358720 sc-358720A | 5 mg 25 mg | $136.00 $541.00 | ||
Direct inhibitor targeting Dynactin 1. Inhibits the ATPase activity of dynein, disrupting the interaction between dynein and Dynactin 1, leading to impaired retrograde transport along microtubules. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Direct inhibitor acting on Dynactin 1 by blocking the GTPase activity of dynamin. This disruption interferes with endocytic processes, affecting the recruitment and function of Dynactin 1 in endosomal trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Indirect inhibitor influencing Dynactin 1 by modulating actin dynamics. Alters actin filament organization, leading to changes in Dynactin 1 recruitment and function during processes such as vesicle trafficking. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Indirect inhibitor modulating Dynactin 1 through myosin II activity. Inhibits myosin II ATPase, affecting the force generation required for Dynactin 1-associated processes, such as vesicular transport along actin filaments. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Indirect inhibitor impacting Dynactin 1 through microtubule destabilization. Disrupts microtubule dynamics, leading to alterations in Dynactin 1 localization and function during processes like retrograde axonal transport. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
Direct inhibitor affecting Dynactin 1 by disrupting the Arp2/3 complex. Inhibits actin nucleation, leading to changes in actin dynamics that influence the recruitment and function of Dynactin 1 during cellular processes involving actin cytoskeleton organization. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Indirect inhibitor influencing Dynactin 1 through actin dynamics. Stabilizes F-actin, leading to alterations in the recruitment and function of Dynactin 1 during processes such as intracellular transport along actin filaments. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Indirect inhibitor modulating Dynactin 1 through Rho-associated protein kinase (ROCK) inhibition. Alters actin cytoskeleton dynamics, affecting Dynactin 1 recruitment and function in processes such as vesicle trafficking along actin filaments. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
Indirect inhibitor influencing Dynactin 1 through Cdc42 inhibition. Alters actin dynamics and organization, leading to changes in Dynactin 1 recruitment and function during cellular processes involving actin cytoskeleton remodeling. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Indirect inhibitor affecting Dynactin 1 through N-WASP inhibition. Modulates actin polymerization dynamics, leading to alterations in Dynactin 1 recruitment and function during cellular processes involving actin cytoskeleton rearrangement. | ||||||