DPYS Activators
DPYS Activators are chemical compounds that indirectly influence the activity of the DPYS (Dihydropyrimidinase) protein, an enzyme pivotal in pyrimidine nucleotide metabolism. The activation of DPYS typically occurs through the modulation of pyrimidine metabolism and nucleotide pools. Compounds like Uracil and Thymine, both pyrimidine nucleobases, can influence DPYS activity by serving as substrates within the pyrimidine catabolic pathway.
Similarly, Orotate, a pyrimidine precursor, affects DPYS indirectly by influencing the metabolic flux within the pyrimidine biosynthetic pathway. Dihydrouracil, a product of DPYS enzymatic action, can also play a role by serving as a substrate for DPYS and potentially influencing its activity in pyrimidine catabolism.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
Zebularine is a DNA methyltransferase inhibitor. Its use can indirectly affect DPYS by altering DNA methylation patterns that may impact gene expression, including genes related to DPYS regulation. | ||||||
Uridine | 58-96-8 | sc-296685 sc-296685A | 1 g 25 g | $61.00 $100.00 | 1 | |
Uracil-1-β-D-ribofuranoside is a ribonucleoside containing uracil. Its presence can indirectly impact DPYS activity by influencing pyrimidine nucleotide levels and the metabolic flux through the pathway. | ||||||