Items 11 to 12 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Fluoro-2′-deoxycytidine | 10356-76-0 | sc-252267 | 5 mg | $70.00 | 1 | |
5-Fluoro-2'-deoxycytidine acts as a Dnmt inhibitor by incorporating into DNA, where it mimics natural nucleotides. This substitution disrupts normal methylation processes, influencing gene regulation. The fluorine atom enhances the compound's stability and alters hydrogen bonding patterns, affecting enzyme affinity. Its unique interactions with Dnmt enzymes can lead to altered reaction kinetics, ultimately impacting epigenetic modifications and cellular processes. | ||||||
SGI-1027 | 1020149-73-8 | sc-473875 | 10 mg | $213.00 | ||
SGI-1027 functions as a Dnmt inhibitor through its ability to form stable complexes with DNA, leading to altered methylation patterns. Its unique structure allows for specific interactions with the active site of Dnmt enzymes, modulating their activity. The compound's distinct electronic properties facilitate enhanced binding affinity, while its steric configuration influences the kinetics of methylation reactions. This results in significant alterations in epigenetic landscapes and gene expression dynamics. | ||||||