| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
RAD51 Inhibitor B02 | 1290541-46-6 | sc-507533 | 10 mg | $95.00 | ||
B02 inhibits DMC1 by disrupting its DNA binding and strand-exchange activities, preventing homologous recombination in DNA repair. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $89.00 $228.00 | ||
Arsenic trioxide disrupts DMC1 function by interfering with the formation of DMC1-ssDNA complexes, hindering homologous recombination in cancer cells. | ||||||
MIRA-1 | 72835-26-8 | sc-204087 sc-204087A | 10 mg 50 mg | $118.00 $452.00 | 1 | |
NSC 19630 inhibits DMC1-mediated homologous recombination by disrupting the DMC1-ssDNA filament formation, preventing DNA repair in cancer cells. | ||||||
Triapine | 200933-27-3 | sc-475303 | 10 mg | $300.00 | ||
Triapine inhibits DMC1 by disrupting ribonucleotide reductase activity, leading to nucleotide pool depletion and reduced DNA repair in cancer cells. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin induces DNA damage and interferes with DMC1's role in DNA repair, contributing to the cytotoxic effects in cancer cells. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Olaparib inhibits PARP1, which interacts with DMC1, thereby preventing efficient homologous recombination and promoting synthetic lethality in cancer cells. | ||||||
NU 1025 | 90417-38-2 | sc-203166 | 5 mg | $131.00 | 9 | |
NU1025 inhibits PARP1, which in turn affects DMC1-mediated DNA repair, making it a potential strategy for cancer therapy. | ||||||
Talazoparib | 1207456-01-6 | sc-507440 | 10 mg | $795.00 | ||
BMN 673 is a PARP inhibitor that disrupts DMC1-mediated DNA repair, promoting the accumulation of DNA damage and cell death in cancer cells. | ||||||
4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one | 1174043-16-3 | sc-497005 | 5 mg | $430.00 | ||
AZD2461 inhibits PARP1, impairing the interaction between PARP1 and DMC1 and sensitizing cancer cells to DNA damage, resulting in cell death. | ||||||