DCAMKL2 Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
XMD 8-92 (free base) | 1234480-50-2 | sc-364068 sc-364068A sc-364068B sc-364068C | 5 mg 10 mg 100 mg 1 g | $235.00 $340.00 $1700.00 $10330.00 | 10 | |
XMD 8-92 (free base) exhibits intriguing properties as a DCAMKL2 modulator, characterized by its ability to engage in specific hydrogen bonding interactions with target proteins. This compound's unique structural features enable it to influence intracellular signaling pathways, promoting distinct conformational changes in protein targets. Its hydrophobic regions enhance membrane permeability, while its electronic characteristics contribute to unique fluorescence properties, allowing for advanced analytical applications. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor could induce hypomethylation of the DCAMKL2 gene promoter, potentially leading to a decrease in gene transcription and subsequent protein synthesis. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid, a histone deacetylase inhibitor, may enhance histone acetylation near the DCAMKL2 gene, potentially resulting in chromatin remodeling and decreased transcriptional activity of the DCAMKL2 gene. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
By inhibiting DNA methyltransferases, RG 108 could specifically prevent the methylation of CpG islands within the DCAMKL2 promoter, possibly resulting in reduced transcriptional initiation and lower protein levels. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine may lead to the demethylation of the DCAMKL2 gene promoter, potentially causing a reduction in transcriptional activity and a subsequent decrease in DCAMKL2 protein levels. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This inhibitor may prevent deacetylation of histones associated with the DCAMKL2 gene, possibly leading to a less compact chromatin structure and a downregulation of gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
By inhibiting the mTOR pathway, Rapamycin could potentially reduce the translation of many mRNAs, which may include the mRNA of DCAMKL2, leading to lower levels of the protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibiting the PI3K/AKT signaling cascade with LY 294002 could lead to a decrease in the transcriptional activity of genes controlled by this pathway, which might include DCAMKL2. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 could stabilize p53, leading to an increased expression of p53-responsive genes that could indirectly lead to the downregulation of the DCAMKL2 gene. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
As a JNK inhibitor, Sp600125 could reduce the activity of transcription factors activated by the JNK pathway, potentially leading to a decrease in DCAMKL2 gene transcription. | ||||||