D19Bwg1357e Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D, a transcription inhibitor, binds to DNA and inhibits RNA synthesis. By disrupting the transcription process, it indirectly influences Pum3, as Pum3 is involved in mRNA binding and regulation. The inhibition of transcription impacts Pum3's ability to interact with target mRNAs, leading to decreased protein expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin, an adenosine analog, inhibits mRNA synthesis by terminating transcription. This indirect inhibition impacts Pum3, as Pum3 is involved in mRNA binding. Cordycepin's action disrupts the synthesis of target mRNAs, diminishing Pum3's ability to regulate gene expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
Fluorouracil, an antimetabolite, interferes with RNA synthesis by inhibiting thymidylate synthase. Its action indirectly influences Pum3, as Pum3 is involved in mRNA binding. By disrupting nucleotide metabolism, 5-Fluorouracil hinders the synthesis of target mRNAs, affecting Pum3's regulatory function on gene expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin, a cyclic peptide, inhibits RNA polymerase II activity, leading to transcriptional arrest. Its indirect impact on Pum3 results from hindering mRNA synthesis, a process central to Pum3's function. Alpha-Amanitin disrupts the synthesis of target mRNAs, affecting Pum3's regulatory role in gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin, an antibiotic, inhibits bacterial RNA polymerase. Its indirect impact on Pum3 is due to the shared eukaryotic RNA polymerase structure. Rifampicin hinders RNA synthesis, influencing Pum3's ability to interact with target mRNAs and regulate gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide, a diterpene triepoxide, inhibits RNA polymerase II-mediated transcription. Its indirect impact on Pum3 arises from the disruption of mRNA synthesis, crucial for Pum3's regulatory role. Triptolide impairs the synthesis of target mRNAs, influencing Pum3's ability to regulate gene expression. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $42.00 $54.00 | 3 | |
6-Thioguanine, a nucleotide analog, disrupts nucleotide metabolism, affecting RNA synthesis. Its indirect impact on Pum3 results from hindering mRNA synthesis, a process central to Pum3's function. Thioguanine impairs the synthesis of target mRNAs, influencing Pum3's ability to interact with and regulate gene expression. | ||||||
6-Mercaptopurine | 50-44-2 | sc-361087 sc-361087A | 50 mg 100 mg | $72.00 $104.00 | ||
6-Mercaptopurine, a purine analog, interferes with nucleotide metabolism, impacting RNA synthesis. Its indirect impact on Pum3 arises from hindering mRNA synthesis, a process central to Pum3's function. 6-Mercaptopurine disrupts the synthesis of target mRNAs, influencing Pum3's ability to interact with and regulate gene expression. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin, a platinum-based chemotherapy drug, forms DNA adducts, disrupting transcription. Its indirect impact on Pum3 results from hindering mRNA synthesis, crucial for Pum3's regulatory role. Cisplatin impairs the synthesis of target mRNAs, influencing Pum3's ability to interact with and regulate gene expression. | ||||||
Methoxsalen (8-Methoxypsoralen) | 298-81-7 | sc-200505 | 1 g | $28.00 | 1 | |
8-Methoxypsoralen, a photosensitizing agent, crosslinks with DNA, inhibiting transcription. Its indirect impact on Pum3 arises from disrupting the transcription process, vital for mRNA synthesis. 8-Methoxypsoralen impairs Pum3's ability to interact with target mRNAs, leading to decreased regulatory control over gene expression. | ||||||