Cytokeratin 2p Activators

Cytokeratin 2p Activators is a class of compounds that can induce the activation of Cytokeratin 2p, either directly or indirectly. These chemicals act by modulating different biochemical pathways that are essential for the function and regulation of keratins in general and Cytokeratin 2p in particular. This class of activators includes various types of compounds, such as retinoids, glucocorticoids, growth factors, and others.

Retinoids like all-trans retinoic acid, and calcitriol, the active form of vitamin D, can induce the differentiation of epithelial cells, leading to an upregulation of keratin expression. This category also includes glucocorticoids like dexamethasone, which can stimulate the expression of keratins in epithelial cells and growth factors like EGF, which can trigger signaling pathways leading to keratinocyte proliferation and differentiation. Further, compounds like caffeine and forskolin are included that can modulate cyclic AMP levels, influencing keratin expression in epithelial cells. Other compounds like PMA, sulforaphane, betulinic acid, lithium chloride, aloe-emodin, and ascorbic acid act on different pathways and cellular processes, leading to changes in keratin expression.