CYP2C9 Inhibitors

CYP2C9 inhibitors belong to a specific chemical class that exerts influence over the activity of the cytochrome P450 enzyme, CYP2C9. These inhibitors play a pivotal role in modulating drug metabolism within the human body. The cytochrome P450 enzyme system is a group of enzymes responsible for the metabolism of a wide array of endogenous and exogenous compounds, including drugs. The chemical class of CYP2C9 inhibitors is characterized by compounds that impede the enzymatic activity of CYP2C9, thereby altering the pharmacokinetics of drugs that are substrates for this enzyme. These inhibitors function by competitively binding to the active site of CYP2C9, either partially or completely obstructing the enzymatic machinery responsible for drug metabolism.