Date published: 2026-1-9

1-800-457-3801

SCBT Portrait Logo
Seach Input

CRF21 Substrates

Santa Cruz Biotechnology now offers a broad range of CRF21 Substrates for use in various applications. CRF21, or corticotropin-releasing factor receptor 2, is a G protein-coupled receptor that plays a significant role in the body's response to stress by mediating the effects of CRF-related peptides. CRF21 Substrates are crucial tools in scientific research for investigating the signaling pathways and molecular mechanisms associated with this receptor. Researchers utilize these substrates to study how CRF21 interacts with its ligands, how it modulates intracellular signaling cascades, and how it influences physiological responses to stress, such as anxiety and behavioral adaptation. These substrates are commonly used in biochemical assays and cell-based studies to measure receptor activity, explore receptor-ligand interactions, and analyze downstream effects on cellular processes such as cAMP production and kinase activation. By employing CRF21 Substrates, scientists can gain insights into the complex regulatory networks that govern stress response, as well as the broader implications of CRF21 signaling in neurobiology and endocrinology. The availability of these substrates has significantly advanced research in fields like neuropharmacology, stress biology, and receptor biology, providing essential tools for dissecting the intricate dynamics of CRF21-mediated signaling pathways. These studies contribute to a deeper understanding of how stress-related signaling impacts cellular and organismal function. View detailed information on our available CRF21 Substrates by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-gamma-Glutamyl-L-alanine

5875-41-2sc-300878
sc-300878A
500 mg
1 g
$316.00
$616.00
1
(0)

L-gamma-Glutamyl-L-alanine acts as a CRF21 by engaging in specific molecular interactions that enhance peptide bond formation. Its unique structure allows for selective binding to amino acid transporters, influencing cellular uptake and metabolism. The compound exhibits distinct reaction kinetics, promoting rapid hydrolysis under physiological conditions. Additionally, it participates in intricate signaling pathways, modulating intracellular calcium levels and affecting cellular homeostasis through its interactions with various receptors.