Date published: 2026-3-12

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L-gamma-Glutamyl-L-alanine (CAS 5875-41-2)

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Alternate Names:
H-GLU(ALA)-OH
Application:
L-gamma-Glutamyl-L-alanine is a compound also known as N-L-R-Glutamyl-L-alanine
CAS Number:
5875-41-2
Molecular Weight:
218.21
Molecular Formula:
C8H14N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-gamma-Glutamyl-L-alanine is a dipeptide that comprises glutamic acid and alanine, which is frequently investigated in biochemistry for its role in peptide absorption and metabolism. Researchers study its involvement in the gamma-glutamyl cycle, a pathway for amino acid transport across cell membranes. This compound is also of interest in enzymology, particularly in the context of gamma-glutamyltransferase (GGT) activity, where it may serve as a substrate or inhibitor, depending on its concentration and the experimental context. In studies related to nutrition and digestion, L-gamma-Glutamyl-L-alanine′s breakdown and utilization provide insights into the efficiency of peptide assimilation. Additionally, its stability and reaction rates under different pH levels and temperatures are examined to understand peptide bond resilience in various environments.


L-gamma-Glutamyl-L-alanine (CAS 5875-41-2) References

  1. Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2.  |  Liu, H., et al. 2013. Acta Crystallogr D Biol Crystallogr. 69: 1470-81. PMID: 23897470
  2. gamma-Glutamylcyclotransferase: inhibition by D-beta-aminoglutaryl-L-alanine and analysis of the solvent kinetic isotope effect.  |  York, MJ., et al. 1989. Eur J Biochem. 184: 97-101. PMID: 2570694
  3. Glutathione metabolism at the blood-cerebrospinal fluid barrier.  |  Anderson, ME., et al. 1989. FASEB J. 3: 2527-31. PMID: 2572501
  4. A spectrophotometric method for the determination of gamma-glutamyl cyclotransferase with alanine dehydrogenase in the presence of anthglutin.  |  Takahashi, T., et al. 1987. Biochem Med Metab Biol. 38: 311-6. PMID: 2893631
  5. Gut microbiota compositional profile and serum metabolic phenotype in patients with primary open-angle glaucoma.  |  Gong, H., et al. 2020. Exp Eye Res. 191: 107921. PMID: 31917963
  6. Metabolomics in Retinal Diseases: An Update.  |  Li, X., et al. 2021. Biology (Basel). 10: PMID: 34681043

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-gamma-Glutamyl-L-alanine, 500 mg

sc-300878
500 mg
$316.00

L-gamma-Glutamyl-L-alanine, 1 g

sc-300878A
1 g
$616.00