CPN reg Activators
Carboxypeptidase N Activators are a curated assortment of chemical compounds that indirectly amplify the functional activity of Carboxypeptidase N through substrate provision and cofactor support. Substrates like Angiotensin II and Bradykinin directly upsurge the catalytic workload of Carboxypeptidase N, thus engaging and enhancing its natural activity. Amino acids such as Lysine and Arginine fortify the activity of Carboxypeptidase N by stabilizing the enzyme-substrate complex, ensuring efficient substrate processing. Furthermore, essential trace elements like Zinc sulfate and Copper(II) sulfate act as pivotal cofactors for Carboxypeptidase N, with zinc being integral to the enzyme's catalytic function, while copper may serve to stabilize its structure, ultimately elevating enzymatic activity. The presence of Calcium chloride and Magnesium chloride is critical for maintaining the enzyme's structural integrity, thus indirectly facilitating an increased rate of catalysis.
Electrolytes such as Sodium chloride and Potassium chloride subtly tune the ionic environment to favor Carboxypeptidase N activity by stabilizing the enzyme-substrate interaction. Cobalt(II) chloride might serve as a zinc surrogate, ensuring that Carboxypeptidase N remains catalytically competent in the potential absence of zinc. The addition of N,N-Dimethylarginine, a competitive inhibitor of nitric oxide synthase, raises the levels of free Arginine, which can benefit Carboxypeptidase N by boosting its substrate access. Collectively, these activators operate through distinct biochemical avenues.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Bradykinin, a substrate for CPN, increases its activity by providing more substrate for cleavage and inactivation, which is one of the main functional roles of Carboxypeptidase N. | ||||||
L-Lysine | 56-87-1 | sc-207804 sc-207804A sc-207804B | 25 g 100 g 1 kg | $95.00 $263.00 $529.00 | ||
Lysine serves as a cofactor for Carboxypeptidase N by stabilizing the active site and enhancing peptide substrate binding, thus indirectly enhancing enzymatic activity. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
Arginine enhances Carboxypeptidase N activity by increasing the stability of the enzyme-substrate complex, as it is often found at the cleavage site of CPN substrates. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc acts as a cofactor for Carboxypeptidase N and is essential for its catalytic activity. Zinc sulfate supplementation can enhance CPN activity by ensuring sufficient cofactor availability. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium ions are necessary for the structural integrity of Carboxypeptidase N, and calcium chloride can enhance CPN activity by maintaining enzyme conformation. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $28.00 $35.00 $48.00 $125.00 | 2 | |
Magnesium ions assist in stabilizing the structure of Carboxypeptidase N and can indirectly enhance enzyme activity by promoting optimal conformation. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $64.00 $176.00 | 7 | |
Cobalt can mimic zinc's role as a cofactor in some enzymes, including CPN. Cobalt(II) chloride can enhance CPN activity by acting as an alternative cofactor. | ||||||
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $19.00 $30.00 $60.00 $110.00 | 15 | |
Sodium ions can influence the ionic environment and stabilize the enzyme-substrate complex, potentially enhancing the activity of Carboxypeptidase N. | ||||||
Potassium Chloride | 7447-40-7 | sc-203207 sc-203207A sc-203207B sc-203207C | 500 g 2 kg 5 kg 10 kg | $55.00 $155.00 $285.00 $455.00 | 5 | |
Potassium ions can modulate the electrostatic environment around Carboxypeptidase N, which may enhance enzyme activity by influencing substrate interaction. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper ions can interact with proteins and potentially stabilize the structure of Carboxypeptidase N, enhancing its activity by maintaining its active conformation. | ||||||