Date published: 2026-4-1

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cortexin 1 Inhibitors

Cortexin 1 inhibitors are chemical compounds designed to specifically target and inhibit the activity of cortexin 1, a protein associated with the development and function of the nervous system, particularly in cortical neurons. Cortexin 1, also known as CTXN1, is primarily expressed in the brain, where it plays a role in regulating neuronal differentiation and synaptic function. This protein is believed to be involved in processes that influence the organization and connectivity of neurons in the cerebral cortex, making it essential for maintaining the structural and functional integrity of neural networks. Although the exact molecular mechanisms of cortexin 1 are still being studied, its involvement in brain development and synaptic plasticity is well-recognized.

Inhibitors of cortexin 1 function by interfering with the protein's role in neuronal signaling pathways or its structural interactions within neurons. These inhibitors might act by binding to specific regions of cortexin 1, preventing it from participating in the assembly of synaptic complexes or disrupting its regulatory function in cortical neuron activity. Through the inhibition of cortexin 1, researchers are able to study the protein's role in neural network formation, synaptic stability, and the regulation of neural signaling pathways. This can shed light on how cortexin 1 contributes to the organization of the cerebral cortex and its influence on higher cognitive functions. Cortexin 1 inhibitors provide valuable tools for dissecting the molecular pathways associated with neuronal development and function, offering insights into the intricate processes that govern cortical neuron activity and brain organization at the cellular level.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

By intercalating DNA, this compound can inhibit transcription, potentially decreasing Cortexin 1 expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methyltransferase inhibitor can alter gene expression patterns, potentially affecting Cortexin 1.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Known to inhibit protein synthesis by blocking translation, which could reduce Cortexin 1 protein levels.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, it can influence gene expression, possibly affecting Cortexin 1.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

This proteasome inhibitor might alter protein degradation rates, potentially influencing Cortexin 1 stability.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

By modulating various cellular pathways, it might indirectly influence Cortexin 1 expression.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Known for its antioxidative properties, it might indirectly influence Cortexin 1 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

As a compound that affects many cellular pathways, it might have indirect effects on Cortexin 1 expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

As a PI3K inhibitor, it could influence cellular signaling pathways that regulate Cortexin 1 expression.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibiting MEK might indirectly influence the cellular pathways that regulate Cortexin 1 expression.