Date published: 2026-4-5

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C3aR Antibodies

Santa Cruz Biotechnology offers a broad range of C3aR monoclonal antibodies for research focused on understanding the complement system in immune responses. C3aR monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA) applications.C3aR, or complement component 3a receptor, plays a critical role in mediating inflammatory responses and modulating immune cell activity. By binding to its ligand, C3a, C3aR influences processes such as chemotaxis, degranulation, and the release of pro-inflammatory cytokines. Understanding C3aR function is essential for elucidating its involvement in various pathological conditions, including autoimmune diseases and infections. Research has shown that C3aR signaling pathways contribute significantly to immune system regulation and inflammatory processes. Recent studies have highlighted C3aR's importance in maintaining immune homeostasis and its potential as a therapeutic target. Investigating C3aR mechanisms can provide valuable insights into disease progression and potential treatment strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of complement system biology and its impact on human health.

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C3aR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

C3aR Antibody (D-12)

sc-133172mouse IgG2a κ183-482 (h)WB, IP, IF, ELISAm, r, h
27
(7)

C3aR Antibody (17)

sc-53782mouse IgG2b κ(h)WB, IP, IF, FCMh
4
(1)

C3aR Antibody (74)

sc-53785mouse IgG1 κ(r)IF, FCMm, r
2
(1)

C3aR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

C3aR CRISPR/Cas9 KO Plasmid (h)

sc-401448hGene KnockoutGFP0
(0)

C3aR HDR Plasmid (h)

sc-401448-HDRhHomology Directed RepairPuromycin0
(0)

C3aR Double Nickase Plasmid (h)

sc-401448-NIChGene KnockoutPuromycin0
(0)

C3aR Double Nickase Plasmid (h2)

sc-401448-NIC-2hGene KnockoutPuromycin0
(0)

C3aR CRISPR/Cas9 KO Plasmid (m)

sc-419392mGene KnockoutGFP0
(0)

C3aR CRISPR Activation Products

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C3aR CRISPR Activation Plasmid (h)

sc-401448-ACThGene ActivationPuro, Blast, Hygro0
(0)

C3aR CRISPR Activation Plasmid (h2)

sc-401448-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

C3aR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

C3aR siRNA (h)

sc-42840hGene SilencingN/A
2
(0)

C3aR shRNA Plasmid (h)

sc-42840-SHhGene SilencingPuromycin
2
(0)

C3aR shRNA (h) Lentiviral Particles

sc-42840-VhGene SilencingPuromycin
2
(0)

C3aR siRNA (m)

sc-42841mGene SilencingN/A0
(0)

C3aR shRNA Plasmid (m)

sc-42841-SHmGene SilencingPuromycin0
(0)

C3aR shRNA (m) Lentiviral Particles

sc-42841-VmGene SilencingPuromycin0
(0)