Date published: 2025-10-19

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CNG Activators

Santa Cruz Biotechnology now offers a broad range of CNG Activators for use in various applications. CNG, or cyclic nucleotide-gated channels, are ion channels that play a crucial role in the transduction of sensory signals, particularly in vision and olfaction, where they respond to changes in intracellular levels of cyclic nucleotides like cAMP and cGMP. CNG Activators are essential tools in scientific research for studying the function of these channels and understanding their role in cellular signaling pathways. Researchers use these activators to investigate how CNG channels regulate ion flow across cell membranes, contributing to the generation of electrical signals in response to sensory stimuli. By modulating the activity of CNG channels, scientists can explore their involvement in various physiological processes, including phototransduction in the retina and signal transduction in olfactory neurons. These activators are also valuable in studies focused on understanding the molecular mechanisms underlying the regulation of CNG channels by cyclic nucleotides, as well as the structural features that dictate their function and gating properties. The availability of CNG Activators has significantly advanced research in neurobiology, cell biology, and physiology, providing critical insights into the role of ion channels in sensory perception and cellular communication. These activators serve as indispensable tools for probing the intricate mechanisms by which CNG channels contribute to the conversion of chemical signals into electrical responses, offering researchers the ability to dissect the dynamic regulation of ion channel activity in a controlled experimental setting. View detailed information on our available CNG Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

8-(4-Chlorophenylthio)guanosine 3′,5′-cyclic Monophosphate sodium salt

51239-26-0sc-202029
sc-202029A
1 mg
5 mg
$45.00
$156.00
(0)

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate sodium salt acts as a potent signaling molecule, influencing various intracellular pathways. Its unique structure allows for specific interactions with protein kinases, modulating enzymatic activity and cellular responses. The compound's cyclic nature contributes to its stability and resistance to hydrolysis, enhancing its efficacy in biochemical assays. Additionally, its solubility in aqueous environments facilitates rapid diffusion across cellular membranes, promoting swift biological effects.