Date published: 2025-10-21

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CIITA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of CIITA monoclonal antibodies for research focused on understanding the Class II Transactivator (CIITA) in immune response regulation. CIITA Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CIITA functions as a transcription factor that regulates the expression of Major Histocompatibility Complex (MHC) class II genes, playing a vital role in the adaptive immune response. By facilitating the presentation of antigens to CD4+ T cells, CIITA is essential for the activation of immune responses against pathogens. Understanding CIITA function provides valuable insights into immune system disorders and potential therapeutic targets. Researchers can explore immune regulation mechanisms through precise detection and analysis of CIITA expression patterns. Advanced visualization techniques enable detailed examination of CIITA localization and interactions within cellular compartments. Comprehensive characterization of CIITA activity supports the development of targeted therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies contribute to advancing immunology research and therapeutic development through reliable, specific detection of CIITA.

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CIITA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CIITA Antibody (7-1H)

sc-13556mouse IgG1 κ1-350 (h)WB, IP, IF, IHC(P)m, r, h
42
(14)

CIITA Antibody (E-12)

sc-376174mouse IgG1 κ831-1130 (h)WB, IP, IF, ELISAm, r, h
3
(1)

CIITA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CIITA CRISPR/Cas9 KO Plasmid (h2)

sc-401762-KO-2hGene KnockoutGFP0
(0)

CIITA HDR Plasmid (h2)

sc-401762-HDR-2hHomology Directed RepairPuromycin0
(0)

CIITA Double Nickase Plasmid (h)

sc-401762-NIChGene KnockoutPuromycin0
(0)

CIITA Double Nickase Plasmid (h2)

sc-401762-NIC-2hGene KnockoutPuromycin0
(0)

CIITA CRISPR/Cas9 KO Plasmid (m2)

sc-419390-KO-2mGene KnockoutGFP0
(0)

CIITA HDR Plasmid (m2)

sc-419390-HDR-2mHomology Directed RepairPuromycin0
(0)

CIITA Double Nickase Plasmid (m)

sc-419390-NICmGene KnockoutPuromycin0
(0)

CIITA Double Nickase Plasmid (m2)

sc-419390-NIC-2mGene KnockoutPuromycin0
(0)

CIITA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CIITA CRISPR Activation Plasmid (h)

sc-401762-ACThGene ActivationPuro, Blast, Hygro0
(0)

CIITA CRISPR Activation Plasmid (h2)

sc-401762-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CIITA Lentiviral Activation Particles (h)

sc-401762-LAChGene ActivationPuro, Blast, Hygro0
(0)

CIITA Lentiviral Activation Particles (h2)

sc-401762-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CIITA CRISPR Activation Plasmid (m)

sc-419390-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CIITA CRISPR Activation Plasmid (m2)

sc-419390-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CIITA Lentiviral Activation Particles (m)

sc-419390-LACmGene ActivationPuro, Blast, Hygro0
(0)

CIITA Lentiviral Activation Particles (m2)

sc-419390-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CIITA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CIITA siRNA (h)

sc-37739hGene SilencingN/A0
(0)

CIITA shRNA Plasmid (h)

sc-37739-SHhGene SilencingPuromycin0
(0)

CIITA shRNA (h) Lentiviral Particles

sc-37739-VhGene SilencingPuromycin0
(0)

CIITA siRNA (m)

sc-37740mGene SilencingN/A0
(0)

CIITA shRNA Plasmid (m)

sc-37740-SHmGene SilencingPuromycin0
(0)

CIITA shRNA (m) Lentiviral Particles

sc-37740-VmGene SilencingPuromycin0
(0)

CIITA siRNA (h2)

sc-270529hGene SilencingN/A0
(0)

CIITA shRNA Plasmid (h2)

sc-270529-SHhGene SilencingPuromycin0
(0)

CIITA shRNA (h2) Lentiviral Particles

sc-270529-VhGene SilencingPuromycin0
(0)