Date published: 2026-4-4

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CFTR Antibodies

Santa Cruz Biotechnology features a diverse variety of CFTR monoclonal antibodies for studying the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR monoclonal antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The CFTR protein plays a crucial role in regulating ion transport across epithelial cell membranes, which is essential for maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a serious genetic disorder that affects the lungs and digestive system. Understanding the function and regulation of CFTR is vital for developing targeted therapies for cystic fibrosis and related diseases. CFTR monoclonal antibodies enable researchers to explore protein expression patterns in various cell types and tissues. Advanced research techniques utilizing CFTR monoclonal antibodies help identify potential therapeutic targets and evaluate treatment effectiveness. Investigating CFTR protein interactions and regulatory pathways provides valuable insights into disease mechanisms and progression. Santa Cruz Biotechnology monoclonal antibodies support the scientific community in advancing cystic fibrosis research and therapeutic development.

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CFTR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CFTR Antibody (A-3)

sc-376683mouse IgG1 κ1419-1457 (h)WB, IP, IF, IHC(P), ELISAm, r, h
18
(10)

CFTR Antibody (GA1)

sc-20074mouse IgG11387-1480 (h)WB, IP, IF, IHC(P)h
2
(3)

CFTR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CFTR CRISPR/Cas9 KO Plasmid (h)

sc-400653hGene KnockoutGFP
1
(2)

CFTR HDR Plasmid (h)

sc-400653-HDRhHomology Directed RepairPuromycin
1
(2)

CFTR Double Nickase Plasmid (h)

sc-400653-NIChGene KnockoutPuromycin
1
(2)

CFTR Double Nickase Plasmid (h2)

sc-400653-NIC-2hGene KnockoutPuromycin
1
(2)

CFTR CRISPR/Cas9 KO Plasmid (m)

sc-419639mGene KnockoutGFP0
(0)

CFTR HDR Plasmid (m)

sc-419639-HDRmHomology Directed RepairPuromycin0
(0)

CFTR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CFTR CRISPR Activation Plasmid (h)

sc-400653-ACThGene ActivationPuro, Blast, Hygro
1
(2)

CFTR Lentiviral Activation Particles (h)

sc-400653-LAChGene ActivationPuro, Blast, Hygro
1
(2)

CFTR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CFTR siRNA (h)

sc-35054hGene SilencingN/A
6
(0)

CFTR shRNA Plasmid (h)

sc-35054-SHhGene SilencingPuromycin
6
(0)

CFTR shRNA (h) Lentiviral Particles

sc-35054-VhGene SilencingPuromycin
6
(0)

CFTR siRNA (m)

sc-35053mGene SilencingN/A
1
(0)

CFTR shRNA Plasmid (m)

sc-35053-SHmGene SilencingPuromycin
1
(0)

CFTR shRNA (m) Lentiviral Particles

sc-35053-VmGene SilencingPuromycin
1
(0)